Literature DB >> 178909

Mechanism of premature polypetide termination in a mouse ascites cell-free system programmed by encephalomyocarditis viral RNA.

L A Hunt.   

Abstract

The premature termination and release of encephalomyocarditis viral RNA-programmed polypeptides were analyzed in a cell-free system from mouse ascites tumor cells. The KCL concentration affects the size distribution of products but not the extent of polypeptide release. The same major products (60,000 to 140,000 molecular weight) are found in both the soluble and particulate fractions. The majority of released polypeptides are free protein, whereas the ribosome-bound product is mostly in the form of peptidyl-tRNA.

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Year:  1976        PMID： 178909      PMCID： PMC515609     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  10 in total

1.  The rate of polypeptide chain elongation in a cell-free system from Krebs II ascites cells.

Authors:  M B Mathews; M Osborn
Journal:  Biochim Biophys Acta       Date:  1974-03-08

2.  Protein synthesis directed by encephalomyocarditis virus mRNA. 3. Discrete polypeptides translated from a monocistronic messenger in vitro.

Authors:  I Boime; P Leder
Journal:  Arch Biochem Biophys       Date:  1972-12       Impact factor: 4.013

3.  The initiation of protein synthesis directed by the RNA from encephalomyocarditis virus.

Authors:  A E Smith
Journal:  Eur J Biochem       Date:  1973-03-01

4.  Initiation of picornavirus protein synthesis in ascites cell extracts.

Authors:  B F Oberg; A J Shatkin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

5.  Protein synthesis directed by encephalomyocarditis virus RNA. II. The in vitro synthesis of high molecular weight proteins and elements of the viral capsid.

Authors:  I Boime; H Aviv; P Leder
Journal:  Biochem Biophys Res Commun       Date:  1971-11-05       Impact factor: 3.575

6.  Virus-specific proteins synthesized in encephalomyocarditis virus-infected HeLa cells.

Authors:  B E Butterworth; L Hall; C M Stoltzfus; R R Rueckert
Journal:  Proc Natl Acad Sci U S A       Date:  1971-12       Impact factor: 11.205

7.  Characterization of the polypeptides formed in response to encephalomyocarditis virus ribonucleic acid in a cell-free system from mouse ascites tumor cells.

Authors:  I M Kerr; R E Brown; D R Tovell
Journal:  J Virol       Date:  1972-07       Impact factor: 5.103

8.  In vitro translation of cardiovirus ribonucleic acid by mammalian cell-free extracts.

Authors:  K L Eggen; A J Shatkin
Journal:  J Virol       Date:  1972-04       Impact factor: 5.103

9.  Studies on the mechanism of polypeptide chain termination in cell-free extracts of E. coli.

Authors:  M C Ganoza; T Nakamoto
Journal:  Proc Natl Acad Sci U S A       Date:  1966-01       Impact factor: 11.205

10.  Mammalian cell-free protein synthesis directed by viral ribonucleic acid.

Authors:  M Mathews; A Korner
Journal:  Eur J Biochem       Date:  1970-12
  10 in total
  2 in total

1.  In vitro translation of Harvey murine sarcoma virus RNA.

Authors:  W P Parks; E M Scolnick
Journal:  J Virol       Date:  1977-06       Impact factor: 5.103

2.  Cell-free synthesis and processing of the proteins of poliovirus.

Authors:  D S Shih; C T Shih; O Kew; M Pallansch; R Rueckert; P Kaesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205
  2 in total

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