| Literature DB >> 178908 |
S Rasheed, A E Freeman, M B Gardner, R J Huebner.
Abstract
Sprague-Dawley and Fischer rat embryo cells became spontaneously transformed about 20 passages after release of endogenous ecotropic type C virus (SD-RaLV and F-RaLV). The virus-producing transformed cells showed loss of contact inhibition, increased growth rate, and tumorigenicity in vivo. Exogenous infection of other Fischer rat embryo cultures in early passage with SD-RaLV and F-RaLV markedly accelerated their rates of transformation.Entities:
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Year: 1976 PMID： 178908 PMCID： PMC515606
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103