Literature DB >> 17890668

Angiogenesis inhibitors and the need for anti-angiogenic therapeutics.

C R Dass1, T M N Tran, P F M Choong.   

Abstract

Angiogenesis is the formation of new blood vessels from pre-existing vessels to form capillary networks, which, among other diseases, such as diabetic retinopathy and macular degeneration, is particularly important for tumor growth and metastasis. Thus, depriving a tumor of its vascular supply by means of anti-angiogenic agents has been of great interest since its proposal in the 1970s. This review looks at the common angiogenic inhibitors (angiostatin, endostatin, maspin, pigment epithelium-derived factor, bevacizumab and other monoclonal antibodies, and zoledronic acid) and their current status in clinical trials.

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Year:  2007        PMID： 17890668     DOI： 10.1177/154405910708601005

Source DB:  PubMed          Journal:  J Dent Res        ISSN： 0022-0345            Impact factor:   6.116


  9 in total

1.  Sprouty2 downregulates angiogenesis during mouse skin wound healing.

Authors:  Mateusz S Wietecha; Lin Chen; Matthew J Ranzer; Kimberly Anderson; Chunyi Ying; Tarun B Patel; Luisa A DiPietro
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-11-12       Impact factor: 4.733

2.  Role of Angiogenesis in Chronic Radiation Proctitis: New Evidence Favoring Inhibition of Angiogenesis Ex Vivo.

Authors:  Peihuang Wu; Li Li; Huaiming Wang; Tenghui Ma; Haiyong Wu; Xinjuan Fan; Zihuan Yang; Daici Chen; Lei Wang
Journal:  Dig Dis Sci       Date:  2017-10-27       Impact factor: 3.199

3.  Delivery of expression constructs of secreted frizzled-related protein 4 and its domains by chitosan-dextran sulfate nanoparticles enhances their expression and anti-cancer effects.

Authors:  Vanathi Perumal; Frank Arfuso; Yan Chen; Simon Fox; Arun M Dharmarajan
Journal:  Mol Cell Biochem       Date:  2017-11-28       Impact factor: 3.396

4.  Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin.

Authors:  Aditi Banerjee; Jing-Yu Lang; Mien-Chie Hung; Krishanu Sengupta; Sushanta K Banerjee; Krishna Baksi; Dipak K Banerjee
Journal:  J Biol Chem       Date:  2011-06-15       Impact factor: 5.157

5.  Recombinant human maspin inhibits high glucose-induced oxidative stress and angiogenesis of human retinal microvascular endothelial cells via PI3K/AKT pathway.

Authors:  Feng Qiu; Huijuan Tong; Yawen Wang; Jun Tao; Hailin Wang; Lei Chen
Journal:  Mol Cell Biochem       Date:  2018-01-23       Impact factor: 3.396

6.  Antitumor activity of placenta-derived mesenchymal stem cells producing pigment epithelium-derived factor in a mouse melanoma model.

Authors:  Qiaoling Chen; Ping Cheng; Na Song; Tao Yin; Hong He; Li Yang; Xiancheng Chen; Yuquan Wei
Journal:  Oncol Lett       Date:  2012-06-22       Impact factor: 2.967

7.  A monoclonal antibody (Mc178-Ab) targeted to the ecto-ATP synthase β-subunit-induced cell apoptosis via a mechanism involving the MAPKase and Akt pathways.

Authors:  Wen-Juan Wang; Zhan Ma; Yi-Wen Liu; Yi-Qing He; Ying-Zhi Wang; Cui-Xia Yang; Yan Du; Mu-Qing Zhou; Feng Gao
Journal:  Clin Exp Med       Date:  2011-04-20       Impact factor: 3.984

8.  Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization.

Authors:  Juan Amaral; S Patricia Becerra
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-10-22       Impact factor: 4.799

9.  Molecular Targeting of VEGF with a Suramin Fragment-DOCA Conjugate by Mimicking the Action of Low Molecular Weight Heparins.

Authors:  Jooho Park; Tae-Bong Kang; Ji-Hong Lim; Hyung-Sik Won
Journal:  Biomolecules       Date:  2020-12-31
  9 in total

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