Literature DB >> 17890090

Can computerised tomography replace bone scintigraphy in detecting bone metastases from breast cancer? A prospective study.

A R Bristow1, A Agrawal, A J Evans, H C Burrell, E J Cornford, J J James, L Hamilton, J F R Robertson, S Y Chan, P A Lawton, K L Cheung.   

Abstract

BACKGROUND: The aim of this study was to determine whether bone scans (BS) can be avoided if pelvis was included in CT thorax and abdomen to detect bony metastases from breast cancer.
MATERIALS AND METHODS: Results of 77 pairs of CT (thorax, abdomen, and pelvis) and BS in newly diagnosed patients with metastatic breast cancer (MBC) were compared prospectively for 12 months. Both scans were blindly assessed by experienced radiologists and discussed at multidisciplinary team meetings regarding the diagnosis of bone metastases.
RESULTS: CT detected metastatic bone lesions in 43 (98%) of 44 patients with bone metastases. The remaining patient had a solitary, asymptomatic bony metastasis in shaft of femur. BS was positive in all patients with bone metastases. There were 11 cases of false positive findings on BS.
CONCLUSION: Our findings suggest routine BS of patients presenting with MBC is not required if CT (thorax, abdomen, and pelvis) is performed.

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Year:  2007        PMID: 17890090     DOI: 10.1016/j.breast.2007.07.042

Source DB:  PubMed          Journal:  Breast        ISSN: 0960-9776            Impact factor:   4.380


  9 in total

1.  Indeterminate lesions on planar bone scintigraphy in lung cancer patients: SPECT, CT or SPECT-CT?

Authors:  Punit Sharma; Rakesh Kumar; Harmandeep Singh; Chandrasekhar Bal; Pramod Kumar Julka; Sanjay Thulkar; Arun Malhotra
Journal:  Skeletal Radiol       Date:  2011-10-16       Impact factor: 2.199

2.  SEOM guidelines for the treatment of bone metastases from solid tumours.

Authors:  Javier Cassinello Espinosa; Aránzazu González Del Alba Baamonde; Fernando Rivera Herrero; Esther Holgado Martín
Journal:  Clin Transl Oncol       Date:  2012-07       Impact factor: 3.405

Review 3.  Diagnosis of bone metastases: a meta-analysis comparing ¹⁸FDG PET, CT, MRI and bone scintigraphy.

Authors:  Hui-Lin Yang; Tao Liu; Xi-Ming Wang; Yong Xu; Sheng-Ming Deng
Journal:  Eur Radiol       Date:  2011-09-02       Impact factor: 5.315

Review 4.  A meta-analysis of 18FDG-PET, MRI and bone scintigraphy for diagnosis of bone metastases in patients with breast cancer.

Authors:  Tao Liu; Tao Cheng; Wen Xu; Wei-Li Yan; Jia Liu; Hui-Lin Yang
Journal:  Skeletal Radiol       Date:  2010-05-22       Impact factor: 2.199

5.  The role of staging Computed Tomography on detection of occult metastasis in asymptomatic breast cancer patients.

Authors:  Chrishanthi Rajasooriyar; Thamayanthy Sritharan; Suvithra Chenthuran; Kavitha Indranath; Rajendra Surenthirakumaran
Journal:  Cancer Rep (Hoboken)       Date:  2020-05-07

6.  Radiological staging in breast cancer: which asymptomatic patients to image and how.

Authors:  T Barrett; D J Bowden; D C Greenberg; C H Brown; G C Wishart; P D Britton
Journal:  Br J Cancer       Date:  2009-09-29       Impact factor: 7.640

7.  Staging Investigations in Breast Cancer: Collective Opinion of UK Breast Surgeons.

Authors:  N Chand; R I Cutress; R S Oeppen; A Agrawal
Journal:  Int J Breast Cancer       Date:  2013-11-20

Review 8.  Multimodal Treatment of Bone Metastasis-A Surgical Perspective.

Authors:  Henry Soeharno; Lorenzo Povegliano; Peter F Choong
Journal:  Front Endocrinol (Lausanne)       Date:  2018-09-07       Impact factor: 5.555

9.  Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients.

Authors:  Nils Martin Bruckmann; Julian Kirchner; Lale Umutlu; Wolfgang Peter Fendler; Robert Seifert; Ken Herrmann; Ann-Kathrin Bittner; Oliver Hoffmann; Svjetlana Mohrmann; Christina Antke; Lars Schimmöller; Marc Ingenwerth; Katharina Breuckmann; Andreas Stang; Christian Buchbender; Gerald Antoch; Lino M Sawicki
Journal:  Eur Radiol       Date:  2021-04-28       Impact factor: 5.315

  9 in total

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