Literature DB >> 1788997

[The effect of increased copper supplements in feed on the development of cadmium residues in swine].

W A Rambeck1, H W Brehm, W E Kollmer.   

Abstract

In commercial pig fattening copper is added to the feed at a concentration exceeding the requirement by a factor of more than ten. This improves the weight gain of the pigs during the first three months remarkably. In order to study the influence of copper supplementation on cadmium retention, 4 groups of male castrated weanling crossbred pigs (Deutsche Landrasse x Pietrain) received for 3 months a diet containing 1 mg Cd per kg feed, given as CdCl2, as well as 0, 50, 100 or 200 mg Cu per kg feed, given as CuSO4. The liver, kidney, spleen, pancreas, brain, heart, diaphragm, bile and duodenal mucosa were submitted to wet ashing and analyzed by atomic absorption spectroscopy for cadmium. The Cd retention in all tissues increased in correlation to the Cu content of the feed. When 200 mg Cu per kg were added, Cd rose in the muscle from 10 to 15 micrograms per kg, in the liver from 770 to 1720 micrograms per kg and in the kidney, where the highest Cd concentration occurred, from 4620 to 9320 micrograms per kg. This indicates that in pigs the retention of cadmium in kidney and in liver is promoted by Cu supplementation as used in commercial pig fattening.

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Year:  1991        PMID: 1788997     DOI: 10.1007/bf01651959

Source DB:  PubMed          Journal:  Z Ernahrungswiss        ISSN: 0044-264X


  5 in total

1.  Cooperative regional studies with growing swine: effects of vitamin E and levels of supplementary copper during the growing-finishing period on gain, feed conversion and tissue copper storage in swine.

Authors: 
Journal:  J Anim Sci       Date:  1974-09       Impact factor: 3.159

2.  Effect of carbadox and various dietary copper levels for weanling swine.

Authors:  M D Roof; D C Mahan
Journal:  J Anim Sci       Date:  1982-11       Impact factor: 3.159

3.  Cadmium-copper interaction in intestinal mucosal cell cytosol of mice.

Authors:  D R Bourcier; R P Sharma; W M Bracken; M J Taylor
Journal:  Biol Trace Elem Res       Date:  1983-06       Impact factor: 3.738

4.  Intestinal metallothionein and the mutual antagonism between copper and zinc in the rat.

Authors:  A C Hall; B W Young; I Bremner
Journal:  J Inorg Biochem       Date:  1979-08       Impact factor: 4.155

5.  Cadmium in induced hair of the rat and its relation to the level in the diet and in the major organs during long-term exposure to cadmium in the subtoxic and toxic range.

Authors:  W E Kollmer
Journal:  J Trace Elem Electrolytes Health Dis       Date:  1991-09
  5 in total
  1 in total

1.  [The effect of vitamin C and zinc on the copper-induced increase of cadmium residues in swine].

Authors:  S Rothe; J Gropp; H Weiser; W A Rambeck
Journal:  Z Ernahrungswiss       Date:  1994-03
  1 in total

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