Literature DB >> 17889483

False-positive Aspergillus antigen testing due to application of piperacillin/tazobactam--is it still an issue?

Olaf Penack1, Patricia Rempf, Barbara Graf, Eckhard Thiel, Igor Wolfgang Blau.   

Abstract

We evaluated the impact of piperacillin/tazobactam (PT) therapy on galactomannan enzyme immunoassay (GEI) testing (Platelia; Bio-Rad, Marnes La Coquette, France). Galactomannan contents of PT batches were highly variable. We found that false-positive GEI results can be avoided by performance of blood sampling before PT administration and by using separate sites for blood sampling and for administration of antibiotics.

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Year:  2007        PMID: 17889483     DOI: 10.1016/j.diagmicrobio.2007.07.020

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


  5 in total

1.  The interaction between piperacillin-tazobactam and Aspergillus galactomannan antigenemia assay: is the story over?

Authors:  G Metan
Journal:  Infection       Date:  2012-09-07       Impact factor: 3.553

2.  Generic piperacillin/tazobactam is not associated with galactomannan false-positivity in adult patients with cancer: a case-control study.

Authors:  J-H Ko; K R Peck; W J Lee; J Y Lee; S Y Cho; Y E Ha; C-I Kang; D R Chung; C W Jung; E-S Kang; J-H Song
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-04-17       Impact factor: 3.267

3.  The interaction between piperacillin/tazobactam and assays for Aspergillus galactomannan and 1,3-beta-D-glucan in patients without risk factors for invasive fungal infections.

Authors:  G Metan; C Ağkuş; H Buldu; A N Koç
Journal:  Infection       Date:  2010-03-17       Impact factor: 3.553

Review 4.  The era of molecular and other non-culture-based methods in diagnosis of sepsis.

Authors:  Nicasio Mancini; Silvia Carletti; Nadia Ghidoli; Paola Cichero; Roberto Burioni; Massimo Clementi
Journal:  Clin Microbiol Rev       Date:  2010-01       Impact factor: 26.132

5.  Drug-laboratory interaction between beta-lactam antibiotics and the galactomannan antigen test used to detect mould infections.

Authors:  Kristin A Otting; Kayla R Stover; John D Cleary
Journal:  Braz J Infect Dis       Date:  2014-05-13       Impact factor: 3.257

  5 in total

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