Literature DB >> 17888962

Permanent chronic atrial fibrillation: is pulmonary vein isolation alone enough?

Wilfried Wisser1, Gernot Seebacher, Tatjana Fleck, Clemens Aigner, Cäsar Khazen, Günter Stix, Doris Hutschala, Ernst Wolner.   

Abstract

BACKGROUND: The efficacy of mere pulmonary vein isolation epicardially for the treatment of permanent chronic atrial fibrillation, in comparison with the left atrial endocardial maze procedure was evaluated.
METHODS: Retrospective data collection and analysis toward the outcome of 72 consecutive patients who underwent left atrial maze procedures between January 2003 and December 2005 was performed. Surgical ablation was performed concomitantly with valve and (or) coronary procedures. Group I (n = 29) received an endocardial left atrial ablation using unipolar saline irrigated radiofrequency (Medtronic Cardioblate surgical ablation pen; Medtronic Inc, Minneapolis, MN). Group II (n = 43) received epicardial isolation of the pulmonary veins using bipolar saline irrigated radiofrequency (Medtronic Cardioblate). Follow-up included 24h electrocardiogram and echocardiography 6 and 12 months postoperatively.
RESULTS: Mean follow-up was 19.5 +/- 1.0 months (17.7 +/- 19.5 months group I vs 20.6 +/- 1.1 months group II). Both groups were comparable with regard to duration of preoperative atrial fibrillation, European system for cardiac operative risk evaluation, left ventricular ejection fraction, aortic cross-clamp time, bypass time, intensive care unit and hospital stay (p > 0.05). No maze procedure-related mortality was observed. In group I, three patients required postoperative pacemaker implantation due to atrioventricular (AV) bloc, bradycardia, and sick sinus syndrome, respectively. In group II, five patients required postoperative pacemaker implantation (three AV bloc and two bradycardia). Freedom from atrial fibrillation at last follow-up was 85.7% and 58.5% in groups I and II, respectively (p = 0.016).
CONCLUSIONS: Pulmonary vein isolation alone seems to be insufficient in treating permanent chronic atrial fibrillation. In case of chronic permanent atrial fibrillation, left atrial endocardial maze, providing the connection lines to the mitral annulus and (or) between the pulmonary veins, seems to be mandatory.

Entities:  

Mesh:

Year:  2007        PMID: 17888962     DOI: 10.1016/j.athoracsur.2007.05.027

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  3 in total

1.  Left atrial ablation for atrial fibrillation: creating the "box lesion" with a bipolar radiofrequency device.

Authors:  Leonid Sternik; Hartzel V Schaff; David Luria; Michael Glikson; Alexander Kogan; Ateret Malachy; Maya First; Ehud Raanani
Journal:  Tex Heart Inst J       Date:  2011

Review 2.  Surgery for atrial fibrillation: recent progress and future perspective.

Authors:  Takashi Nitta; Yosuke Ishii; Shun-Ichiro Sakamoto
Journal:  Gen Thorac Cardiovasc Surg       Date:  2012-01-13

Review 3.  Current status of the surgical treatment of atrial fibrillation.

Authors:  Alexander S Geha; Khaled Abdelhady
Journal:  World J Surg       Date:  2008-03       Impact factor: 3.352

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.