BACKGROUND: To evaluate visual field changes in patients with Parkinson's disease. METHODS: Standard automated perimetry of 14 patients (28 eyes) with Parkinson's disease (PD) were compared with controls. PD patients with Unified Parkinson's Disease Rating Scale (UPDRS) score below 25 were included in the study. RESULTS: Visual field indices including mean deviation (-4.69+/-2.72 vs. -1.71+/-1.30, p=0.0008), pattern standard deviation (3.94+/-1.94 vs. 2.30+/-0.41, p=0.001), and corrected pattern standard deviation (3.23+/-2.18 vs. 1.20+/-0.91, p=0.003), were significantly worse in patients with PD when compared with the control group. Bilateral glaucoma-like visual field defects were evident in six patients. CONCLUSION: Parkinson's patients had worse visual field indices suggesting a common insult in the etiopathogenesis of nerve fiber layer damages observed in glaucoma and PD.
BACKGROUND: To evaluate visual field changes in patients with Parkinson's disease. METHODS: Standard automated perimetry of 14 patients (28 eyes) with Parkinson's disease (PD) were compared with controls. PDpatients with Unified Parkinson's Disease Rating Scale (UPDRS) score below 25 were included in the study. RESULTS: Visual field indices including mean deviation (-4.69+/-2.72 vs. -1.71+/-1.30, p=0.0008), pattern standard deviation (3.94+/-1.94 vs. 2.30+/-0.41, p=0.001), and corrected pattern standard deviation (3.23+/-2.18 vs. 1.20+/-0.91, p=0.003), were significantly worse in patients with PD when compared with the control group. Bilateral glaucoma-like visual field defects were evident in six patients. CONCLUSION:Parkinson'spatients had worse visual field indices suggesting a common insult in the etiopathogenesis of nerve fiber layer damages observed in glaucoma and PD.
Authors: M Dominik Fischer; Matthis Synofzik; Christoph Kernstock; Janko Dietzsch; Robert Heidlauf; Julia Schicks; Karin Srulijes; Sarah Wiethoff; Oliver Menn; Daniela Berg; Ludger Schöls; Ulrich Schiefer Journal: Graefes Arch Clin Exp Ophthalmol Date: 2012-08-10 Impact factor: 3.117
Authors: Kari B Green-Church; Igor Butovich; Mark Willcox; Douglas Borchman; Friedrich Paulsen; Stefano Barabino; Ben J Glasgow Journal: Invest Ophthalmol Vis Sci Date: 2011-03-30 Impact factor: 4.799
Authors: Sarah F Janssen; Theo G M F Gorgels; Koen Bossers; Jacoline B Ten Brink; Anke H W Essing; Martijn Nagtegaal; Peter J van der Spek; Nomdo M Jansonius; Arthur A B Bergen Journal: PLoS One Date: 2012-09-18 Impact factor: 3.240