Literature DB >> 17888700

A randomized study of the effect of 5-year and lifetime hip fracture risk information on physician recommendations for management of low bone density.

Joan M Neuner1, Purushottam W Laud, Marilyn M Schapira.   

Abstract

Although risk prediction tools providing absolute fracture risk information are currently under development, little is known about US physicians' current thresholds for osteoporosis treatment or the potential effect of fracture risk information on treatment decisions. To investigate this, a random sample of US primary care physicians was surveyed. Treatment recommendations for 4 patient scenarios depicting postmenopausal women of varying ages, weights, and bone mineral density (BMD) were elicited. Physicians were randomly assigned to receive all scenarios with either a basic BMD report or an augmented BMD report containing 5-yr and lifetime absolute hip fracture risk estimates. Over 95% of physicians recommended prescription pharmacologic treatment of a 70-yr-old patient with osteoporosis. For 3 scenarios depicting women with T-scores of -1.01, treatment recommendations ranged from 30% to 44%. There were no statistically significant differences between physicians who received augmented and basic BMD reports, although those with augmented BMD reports were less likely to recommend prescription treatments. Physician specialty had inconsistent and small effects on recommendations. We conclude that nearly all of a random sample of US primary care physicians recommend pharmacologic treatment of osteoporosis, but a substantial minority also recommend treatment for patients who would not fit current guidelines. A BMD report including absolute hip fracture risk estimates did not change treatment recommendations.

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Year:  2007        PMID: 17888700      PMCID: PMC4098647          DOI: 10.1016/j.jocd.2007.07.005

Source DB:  PubMed          Journal:  J Clin Densitom        ISSN: 1094-6950            Impact factor:   2.617


  24 in total

Review 1.  Why don't physicians follow clinical practice guidelines? A framework for improvement.

Authors:  M D Cabana; C S Rand; N R Powe; A W Wu; M H Wilson; P A Abboud; H R Rubin
Journal:  JAMA       Date:  1999-10-20       Impact factor: 56.272

2.  American Association of Clinical Endocrinologists 2001 Medical Guidelines for Clinical Practice for the Prevention and Management of Postmenopausal Osteoporosis.

Authors: 
Journal:  Endocr Pract       Date:  2001 Jul-Aug       Impact factor: 3.443

3.  Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).

Authors: 
Journal:  JAMA       Date:  2001-05-16       Impact factor: 56.272

4.  Failure to diagnose and treat osteoporosis in elderly patients hospitalized with hip fracture.

Authors:  H K Kamel; M S Hussain; S Tariq; H M Perry; J E Morley
Journal:  Am J Med       Date:  2000-09       Impact factor: 4.965

5.  Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds.

Authors:  J A Kanis; O Johnell; A Oden; A Dawson; C De Laet; B Jonsson
Journal:  Osteoporos Int       Date:  2001-12       Impact factor: 4.507

6.  An assessment tool for predicting fracture risk in postmenopausal women.

Authors:  D M Black; M Steinbuch; L Palermo; P Dargent-Molina; R Lindsay; M S Hoseyni; O Johnell
Journal:  Osteoporos Int       Date:  2001       Impact factor: 4.507

7.  Comparison of vignettes, standardized patients, and chart abstraction: a prospective validation study of 3 methods for measuring quality.

Authors:  J W Peabody; J Luck; P Glassman; T R Dresselhaus; M Lee
Journal:  JAMA       Date:  2000-04-05       Impact factor: 56.272

8.  Bone density testing in older women and its association with patient age.

Authors:  Joan M Neuner; Neil Binkley; Rodney A Sparapani; Purushottam W Laud; Ann B Nattinger
Journal:  J Am Geriatr Soc       Date:  2006-03       Impact factor: 5.562

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Journal:  J Bone Miner Res       Date:  1992-06       Impact factor: 6.741

10.  Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group.

Authors:  S R Cummings; M C Nevitt; W S Browner; K Stone; K M Fox; K E Ensrud; J Cauley; D Black; T M Vogt
Journal:  N Engl J Med       Date:  1995-03-23       Impact factor: 91.245

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  3 in total

1.  Patient perceptions of osteoporosis treatment thresholds.

Authors:  Joan M Neuner; Marilyn M Schapira
Journal:  J Rheumatol       Date:  2014-02-01       Impact factor: 4.666

2.  Physicians' perspectives on the treatment of osteoporosis patients with bisphosphonates.

Authors:  Tao Gu; Debra F Eisenberg Lawrence; Judith J Stephenson; Jingbo Yu
Journal:  Clin Interv Aging       Date:  2016-02-15       Impact factor: 4.458

Review 3.  Bone Mineral Density in Schizophrenia: An Update of Current Meta-Analysis and Literature Review Under Guideline of PRISMA.

Authors:  Ping-Tao Tseng; Yen-Wen Chen; Pin-Yang Yeh; Kun-Yu Tu; Yu-Shian Cheng; Ching-Kuan Wu
Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.817

  3 in total

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