| Literature DB >> 17888465 |
Lidiane Gaspareto Felippe1, Debora Cristina Baldoqui, Massuo Jorge Kato, Vanderlan da Silva Bolzani, Elsie Franklin Guimarães, Regina Maria Barreto Cicarelli, Maysa Furlan.
Abstract
Five tetrahydrofuran lignans and two known flavones were isolated from the aerial parts of Peperomia blanda. The structures of the isolated lignans were elucidated by interpretation of their spectroscopic data, including by gHMQC and gHMBC. The relative and absolute configurations of the isolates were determined from NOESY interactions and optical properties, respectively. Four of the lignans were diastereomeric whilst one was of mixed biosynthetic origin. All but one of the lignans exhibited high in vitro trypanocidal activity when assayed against epimastigotes of Trypanosoma cruzi strain Y.Entities:
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Year: 2007 PMID： 17888465 DOI： 10.1016/j.phytochem.2007.08.012
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072