Literature DB >> 17887713

Tailoring nanoparticle surface chemistry to enhance laser desorption ionization of peptides and proteins.

Edward T Castellana1, David H Russell.   

Abstract

Gold nanoparticles capped with 4-aminothiophenol have been employed for laser desorption ionization mass spectrometry of biomolecules. We demonstrate that the capped nanoparticles increase ion yields, decrease ion fragmentation, and increase the useful analyte mass range when compared to other nanoparticle systems. These results will allow for further development of nanoparticles with both targeting and enhanced ionization abilities to aid in biomarker screening.

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Year:  2007        PMID： 17887713     DOI： 10.1021/nl071469w

Source DB:  PubMed          Journal:  Nano Lett        ISSN： 1530-6984            Impact factor:   11.189


  15 in total

1.  Inkjet-printed gold nanoparticle surfaces for the detection of low molecular weight biomolecules by laser desorption/ionization mass spectrometry.

Authors:  Alyssa L M Marsico; Brian Creran; Bradley Duncan; S Gokhan Elci; Ying Jiang; Timothy B Onasch; Joda Wormhoudt; Vincent M Rotello; Richard W Vachet
Journal:  J Am Soc Mass Spectrom       Date:  2015-07-23       Impact factor: 3.109

2.  Biomimetic antireflective silicon nanocones array for small molecules analysis.

Authors:  Yandong Wang; Zhoufang Zeng; Jie Li; Lifeng Chi; Xinhua Guo; Nan Lu
Journal:  J Am Soc Mass Spectrom       Date:  2012-12-19       Impact factor: 3.109

3.  Evaluation of nanoporous gold with controlled surface structures for laser desorption ionization (LDI) analysis: surface area versus LDI signal intensity.

Authors:  Jang Mi Jin; Suhee Choi; Young Hwan Kim; Man Ho Choi; Jongwon Kim; Sunghwan Kim
Journal:  J Am Soc Mass Spectrom       Date:  2012-07-24       Impact factor: 3.109

4.  Functional microgels assisted tryptic digestion and quantification of cytochrome c through internal standard mass spectrometry.

Authors:  Li-Yi Chen; Wei-Cheng Wu; Huan-Tsung Chang
Journal:  J Am Soc Mass Spectrom       Date:  2014-09-26       Impact factor: 3.109

Review 5.  Nanoparticle assisted laser desorption/ionization mass spectrometry for small molecule analytes.

Authors:  Hani Nasser Abdelhamid
Journal:  Mikrochim Acta       Date:  2018-03-01       Impact factor: 5.833

6.  Gold Nanoparticles (AuNPs) as Reactive Matrix for Detection of Trace Levels of HCN in Air by Laser Desorption/Ionization Mass Spectrometry (LDI-MS).

Authors:  Julius Pavlov; Athula B Attygalle
Journal:  J Am Soc Mass Spectrom       Date:  2019-03-07       Impact factor: 3.109

7.  Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review.

Authors:  Hani Nasser Abdelhamid
Journal:  Mikrochim Acta       Date:  2019-09-13       Impact factor: 5.833

8.  Protons are one of the limiting factors in determining sensitivity of nano surface-assisted (+)-mode LDI MS analyses.

Authors:  Eunji Cho; Miri Ahn; Young Hwan Kim; Jongwon Kim; Sunghwan Kim
Journal:  J Am Soc Mass Spectrom       Date:  2013-08-18       Impact factor: 3.109

9.  CHCA-modified Au nanoparticles for laser desorption ionization mass spectrometric analysis of peptides.

Authors:  Jicheng Duan; Matthew J Linman; Chih-Yuan Chen; Quan J Cheng
Journal:  J Am Soc Mass Spectrom       Date:  2009-04-18       Impact factor: 3.109

10.  Multiplexed screening of cellular uptake of gold nanoparticles using laser desorption/ionization mass spectrometry.

Authors:  Zheng-Jiang Zhu; Partha S Ghosh; Oscar R Miranda; Richard W Vachet; Vincent M Rotello
Journal:  J Am Chem Soc       Date:  2008-10-01       Impact factor: 15.419
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