Literature DB >> 17885844

A new anti-HIV lupane acid from Gleditsia sinensis Lam.

Wan-Hua Li1, Xiang-Ming Zhang, Rong-Ren Tian, Yong-Tang Zheng, Wen-Ming Zhao, Ming-Hua Qiu.   

Abstract

A new lupane acid, 2beta-carboxyl,3beta-hydroxyl-norlupA (1)-20 (29)-en-28-oic acid (1), together with five known lupane acid derivatives (2-6), were isolated from the stings of Gleditsia sinensis Lam.. Their structures were elucidated on the basis of 1D and 2D NMR techniques. All these known compounds were isolated from this genus for the first time. The new compound 1 showed strong anti-HIV activity.

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Year:  2007        PMID： 17885844     DOI： 10.1080/10286020600883419

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  7 in total

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Review 2.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

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Review 3.  From Traditional Usage to Pharmacological Evidence: A Systematic Mini-Review of Spina Gleditsiae.

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Journal:  Evid Based Complement Alternat Med       Date:  2016-06-28       Impact factor: 2.629

4.  Ethanol extract of Gleditsia sinensis thorn suppresses angiogenesis in vitro and in vivo.

Authors:  Jin-Mu Yi; Jong-Shik Park; Se-Mi Oh; Jun Lee; Jinhee Kim; Dal-Seok Oh; Ok-Sun Bang; No Soo Kim
Journal:  BMC Complement Altern Med       Date:  2012-12-04       Impact factor: 3.659

5.  Gleditsia sinensis Thorn Attenuates the Collagen-Based Migration of PC3 Prostate Cancer Cells through the Suppression of α2β1 Integrin Expression.

Authors:  Sujin Ryu; Ki Moon Park; Seung Ho Lee
Journal:  Int J Mol Sci       Date:  2016-03-02       Impact factor: 5.923

6.  The Synergic Anti-inflammatory Impact of Gleditsia sinensis Lam. and Lactobacillus brevis KY21 on Intestinal Epithelial Cells in a DSS-induced Colitis Model.

Authors:  Younghoon Kim; Ji Hoon Koh; Young Jun Ahn; Sejong Oh; Sea Hun Kim
Journal:  Korean J Food Sci Anim Resour       Date:  2015-10-31       Impact factor: 2.622

7.  GT198 Is a Target of Oncology Drugs and Anticancer Herbs.

Authors:  Junfeng Pang; Jie Gao; Liyong Zhang; Nahid F Mivechi; Lan Ko
Journal:  Front Oral Health       Date:  2021-06-11
  7 in total

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