| Literature DB >> 17884236 |
Alberto Landi1, Alberto Mazzoldi, Chiara Andreoni, Matteo Bianchi, Andrea Cavallini, Marco Laurino, Leonardo Ricotti, Rodolfo Iuliano, Barbara Matteoli, Luca Ceccherini-Nelli.
Abstract
Various models of HIV infection and evolution have been considered in the literature. This paper considers a variant of the Wodarz and Nowak mathematical model, adding "aggressiveness" as a new state variable in order to quantify the strength of the virus and its response to drugs. Although the model proposed is relatively simple, simulation results suggest that it may be useful in predicting the impact of the effectiveness of therapy on HIV dynamics.Entities:
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Year: 2007 PMID： 17884236 DOI： 10.1016/j.cmpb.2007.08.003
Source DB: PubMed Journal: Comput Methods Programs Biomed ISSN： 0169-2607 Impact factor: 5.428