Literature DB >> 17884171

Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor.

Carol L Shields1, Benjamin Perez, Miguel A Materin, Sonul Mehta, Jerry A Shields.   

Abstract

PURPOSE: To evaluate the retinal status overlying choroidal osteoma using optical coherence tomography (OCT).
DESIGN: Retrospective noncomparative case series. PARTICIPANTS: Twenty-two eyes with choroidal osteoma.
METHODS: Choroidal osteoma was studied with fundus photography, ultrasonography, and OCT. MAIN OUTCOME MEASURE: Retinal status over the calcified and decalcified portions of choroidal osteoma.
RESULTS: There were 8 completely calcified and 14 partially decalcified choroidal osteomas. Optical coherence tomography was performed over the calcified portion in 21 eyes and over the decalcified portion in 10 eyes. The calcified portion displayed an overlying intact inner retina (n = 21 [100%]), intact outer retina (n = 20 [95%]), and intact photoreceptor layer (n = 21 [100%]). In contrast, the decalcified portion showed an intact inner retina (n = 9 [90%]) and markedly thinned to absent outer retina and photoreceptor layers (n = 10 [100%]). Of the 18 eyes with subfoveolar choroidal osteoma, visual acuity (VA) was 20/20 to 20/50 in all 11 eyes with calcified tumor, and OCT confirmed preservation of retinal architecture. In contrast, VA was 20/200 or worse in all 7 eyes with subfoveolar decalcified tumor, correlating with OCT findings of outer retinal thinning and photoreceptor loss.
CONCLUSIONS: The retina shows profound outer layer thinning and photoreceptor loss over decalcified choroidal osteoma. These findings correlate with poor VA over decalcified subfoveolar choroidal osteoma compared with good VA over calcified subfoveolar tumor.

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Mesh:

Year:  2007        PMID: 17884171     DOI: 10.1016/j.ophtha.2007.07.037

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  22 in total

1.  Progression of Anterograde Trans-Synaptic Degeneration in the Human Retina Is Modulated by Axonal Convergence and Divergence.

Authors:  E L Panneman; D Coric; L M D Tran; W A E J de Vries-Knoppert; A Petzold
Journal:  Neuroophthalmology       Date:  2019-05-27

2.  Rescue therapy with intravitreal aflibercept for choroidal neovascularization secondary to choroidal osteoma non-responder to intravitreal bevacizumab and ranibizumab.

Authors:  Andrea Saitta; Michele Nicolai; Piergiorgio Neri; Michele Reibaldi; Alfonso Giovannini; Cesare Mariotti
Journal:  Int Ophthalmol       Date:  2015-03-12       Impact factor: 2.031

3.  [Choroidal neovascularisation in a patient with choroidal osteoma visualized by OCT angiography].

Authors:  N Mihailovic; M Alnawaiseh; R-L Merté; N Eter
Journal:  Ophthalmologe       Date:  2017-09       Impact factor: 1.059

4.  [Newly occurring loss of visual acuity in choroidal osteoma].

Authors:  A Schuh; P Foerster; S Priglinger; K Eibl-Lindner
Journal:  Ophthalmologe       Date:  2018-03       Impact factor: 1.059

5.  [Manifestation of bilateral choroidal osteoma in childhood. Progressive myopia due to staphyloma posticum].

Authors:  J Heichel; T Bredehorn-Mayr; U Stuhlträger; K S Kunert; M Jäger; B Lorenz
Journal:  Ophthalmologe       Date:  2016-02       Impact factor: 1.059

6.  Multimodal imaging in choroidal osteomas.

Authors:  Sugandha Goel; Sudipta Das; A Joash Rijey; Debmalya Das
Journal:  GMS Ophthalmol Cases       Date:  2022-02-25

7.  Case Report: Multimodal Imaging in a Rare Case of Morning Glory Disc Anomaly Complicated With Choroidal Ossification.

Authors:  Shuya Wang; Xingrong Wang; Ying Wang; Hongsheng Bi
Journal:  Front Med (Lausanne)       Date:  2022-05-16

8.  Optical coherence tomography of retinal and choroidal tumors.

Authors:  Emil Anthony T Say; Sanket U Shah; Sandor Ferenczy; Carol L Shields
Journal:  J Ophthalmol       Date:  2011-07-18       Impact factor: 1.909

9.  Decalcified choroidal osteoma found in the retina.

Authors:  Tadanobu Yoshikawa; Kanji Takahashi
Journal:  Clin Ophthalmol       Date:  2012-11-02

10.  Optical coherence tomography of retinal and choroidal tumors.

Authors:  Emil Anthony T Say; Sanket U Shah; Sandor Ferenczy; Carol L Shields
Journal:  J Ophthalmol       Date:  2011-06-08       Impact factor: 1.909

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