| Literature DB >> 17884122 |
Vânia M A Moreira1, Tadas S Vasaitis, Vincent C O Njar, Jorge A R Salvador.
Abstract
A series of novel 1H- and 2H-indazole derivatives of the commercially available dehydroepiandrosterone acetate have been synthesized and tested for inhibition of human cytochrome 17alpha-hydroxylase-C(17,20)-lyase (CYP17), androgen receptor (AR) binding affinity, and cytotoxic potential against three prostate cancer (PC) cell lines.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17884122 DOI： 10.1016/j.steroids.2007.08.004
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668