| Literature DB >> 17883211 |
G C Chopra1, B D Sleeman, J Brindley, D G Knapp, A V Holden.
Abstract
Normal cardiac muscle contraction occurs in response to a rapid rise followed by a slower decay in intracellular calcium concentration. When cardiac muscle cells are loaded with calcium, an intracellular store releases calcium into the cytosol by the process of calcium-induced calcium release (CICR). This release contributes to the rise in intracellular calcium which in turn triggers contraction. We use two qualitative piecewise linear reaction-diffusion models of this behaviour to investigate the speed, stability and waveform of plane waves using singular perturbation techniques.Entities:
Mesh:
Year: 1999 PMID: 17883211 DOI: 10.1006/bulm.1998.0081
Source DB: PubMed Journal: Bull Math Biol ISSN: 0092-8240 Impact factor: 1.758