Literature DB >> 17880846

Is the septic response good or bad?

Willem Joost Wiersinga1, Tom van der Poll.   

Abstract

A careful balance between the inflammatory and anti-inflammatory response is vital in order to survive the daily invasion of pathogens. Sepsis has always been regarded as the result of an exacerbated detrimental inflammatory response towards invading bacteria. However, recent insights have forced us to rethink this sepsis paradigm. This review discusses the latest trends and developments in the sepsis field and helps to set the stage for the current debate on whether the sepsis response is good or bad.

Entities:  

Year:  2007        PMID： 17880846     DOI： 10.1007/s11908-007-0057-5

Source DB:  PubMed          Journal:  Curr Infect Dis Rep        ISSN： 1523-3847            Impact factor:   3.725


  52 in total

1.  Protection from septic shock by neutralization of macrophage migration inhibitory factor.

Authors:  T Calandra; B Echtenacher; D L Roy; J Pugin; C N Metz; L Hültner; D Heumann; D Männel; R Bucala; M P Glauser
Journal:  Nat Med       Date:  2000-02       Impact factor: 53.440

2.  ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.

Authors:  Yousef Al-Abed; Darrin Dabideen; Bayan Aljabari; Aline Valster; Davorka Messmer; Mahendar Ochani; Mahira Tanovic; Kanta Ochani; Michael Bacher; Ferdinando Nicoletti; Christine Metz; Valentin A Pavlov; Edmund J Miller; Kevin J Tracey
Journal:  J Biol Chem       Date:  2005-08-22       Impact factor: 5.157

Review 3.  Physiology and immunology of the cholinergic antiinflammatory pathway.

Authors:  Kevin J Tracey
Journal:  J Clin Invest       Date:  2007-02       Impact factor: 14.808

Review 4.  2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.

Authors:  Mitchell M Levy; Mitchell P Fink; John C Marshall; Edward Abraham; Derek Angus; Deborah Cook; Jonathan Cohen; Steven M Opal; Jean-Louis Vincent; Graham Ramsay
Journal:  Crit Care Med       Date:  2003-04       Impact factor: 7.598

5.  Antithrombin-III prevents the lethal effects of Escherichia coli infusion in baboons.

Authors:  F B Taylor; T E Emerson; R Jordan; A K Chang; K E Blick
Journal:  Circ Shock       Date:  1988-11

6.  Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia.

Authors:  K J Tracey; Y Fong; D G Hesse; K R Manogue; A T Lee; G C Kuo; S F Lowry; A Cerami
Journal:  Nature       Date:  1987 Dec 17-23       Impact factor: 49.962

7.  Early inhibition of activated fibrinolysis predicts microbial infection, shock and mortality in febrile medical patients.

Authors:  J Raaphorst; A B Johan Groeneveld; A W Bossink; C Erik Hack
Journal:  Thromb Haemost       Date:  2001-08       Impact factor: 5.249

8.  Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

Authors:  F B Taylor; A Chang; C T Esmon; A D'Angelo; S Vigano-D'Angelo; K E Blick
Journal:  J Clin Invest       Date:  1987-03       Impact factor: 14.808

9.  Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.

Authors:  Judith Branger; Sylvia Knapp; Sebastiaan Weijer; Jaklien C Leemans; Jennie M Pater; Peter Speelman; Sandrine Florquin; Tom van der Poll
Journal:  Infect Immun       Date:  2004-02       Impact factor: 3.441

10.  Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.

Authors:  Hong Wang; Man Yu; Mahendar Ochani; Carol Ann Amella; Mahira Tanovic; Seenu Susarla; Jian Hua Li; Haichao Wang; Huan Yang; Luis Ulloa; Yousef Al-Abed; Christopher J Czura; Kevin J Tracey
Journal:  Nature       Date:  2002-12-22       Impact factor: 49.962
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  2 in total

1.  Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.

Authors:  Gavin C K W Koh; Rapeephan R Maude; M Fernanda Schreiber; Direk Limmathurotsakul; W Joost Wiersinga; Vanaporn Wuthiekanun; Sue J Lee; Weera Mahavanakul; Wipada Chaowagul; Wirongrong Chierakul; Nicholas J White; Tom van der Poll; Nicholas P J Day; Gordon Dougan; Sharon J Peacock
Journal:  Clin Infect Dis       Date:  2011-02-03       Impact factor: 9.079

2.  MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei.

Authors:  W Joost Wiersinga; Catharina W Wieland; Joris J T H Roelofs; Tom van der Poll
Journal:  PLoS One       Date:  2008-10-23       Impact factor: 3.240
  2 in total

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