Literature DB >> 17878084

Interaction between sodium hypochlorite and chlorhexidine gluconate.

Bettina R Basrani1, Sheela Manek, Rana N S Sodhi, Edward Fillery, Aldo Manzur.   

Abstract

The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) results in the formation of a precipitate. The aim of this study was to determine the minimum concentration of NaOCl required to form a precipitate with 2.0% CHX. This was accomplished with a serial dilution technique. X-ray photon spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) were used to qualify and quantify the precipitate. A color change and precipitate were induced in 2.0% CHX by 0.023% and 0.19% NaOCl, respectively. Both XPS and TOF-SIMS showed the presence of para-chloroaniline in an amount directly related to the concentration of NaOCl used. Until this precipitate is studied further, its formation should be avoided by removing the NaOCl before placing CHX into the canal.

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Year:  2007        PMID: 17878084     DOI: 10.1016/j.joen.2007.04.001

Source DB:  PubMed          Journal:  J Endod        ISSN: 0099-2399            Impact factor:   4.171


  48 in total

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