Literature DB >> 17877664

Selection bias in enrollment to a programme aimed at the secondary prevention of ischaemic heart disease in general practice: a cohort study.

B Buckley1, A W Murphy, L Glynn, C Hennigan.   

Abstract

OBJECTIVE: To evaluate differences between adults who participated in a secondary prevention of ischaemic heart disease (IHD) programme and those who did not.
DESIGN: Population-based cohort study.
SETTING: A random selection of 12 Irish general practices. PARTICIPANTS: A total of 493 adults with IHD identified in 2000/2001. INTERVENTION: Medical records search and postal questionnaires in 2000/2001 and 2005/2006. MAIN OUTCOME MEASURES: Differences in demographic characteristics and indicators of process of care and risk factor management between participants and non-participants.
RESULTS: Multiple logistic regression confirmed that female gender was associated with a reduced likelihood of participation in the secondary prevention programme [odds ratio (OR) 0.53 (95% CI: 0.32-0.87)], while an adequately controlled total cholesterol level was associated with an increased likelihood of enrollment [OR 1.82 (95% CI: 1.18-2.80)].
CONCLUSIONS: There is limited evidence that biases, which have been shown to affect participation in research, also affect participation in care programmes in everyday practice. A gender bias appears to have affected the enrollment of participants for the secondary preventive programme considered by this study, with enrollment favouring men with well-managed cholesterol. Reimbursement dependent upon patient adherence may incentivise the enrollment of adherent patients, although the influence of patient choice is unclear: the need to maintain records relating to patients who opt out of such interventions is thus highlighted.

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Year:  2007        PMID: 17877664     DOI: 10.1111/j.1742-1241.2007.01548.x

Source DB:  PubMed          Journal:  Int J Clin Pract        ISSN: 1368-5031            Impact factor:   2.503


  2 in total

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Authors:  Krista C van den Broek; Ivan Nyklíček; Johan Denollet
Journal:  Int J Behav Med       Date:  2011-03

2.  Use of exercise tests in primary care: importance for referral decisions and possible bias in the decision process; a prospective observational study.

Authors:  Gunnar Nilsson; Thomas Mooe; Lars Söderström; Eva Samuelsson
Journal:  BMC Fam Pract       Date:  2014-11-30       Impact factor: 2.497

  2 in total

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