OBJECTIVE: The present study investigated the predictive power of anxiety, IQ, severity of ADHD and parental depression on the outcome of treatment in children with ADHD. METHOD: Fifty children with ADHD (ages 8-12) were randomized to a 10-week treatment of methylphenidate or to a treatment of methylphenidate combined with multimodal behavior therapy. Prior to treatment predictors were assessed. Outcome was assessed separately for parents and teachers on a composite measure of inattentive, hyperactive, oppositional- and conduct disorder symptoms. RESULTS: There was neither a significant difference between the two treatments at baseline nor did treatment condition predict outcome. Therefore the data were collapsed across the two treatments. A combination of anxiety and IQ predicted teacher-rated outcome, explaining 18% of the variance. Higher anxiety and higher IQ's indicated better treatment outcome. There were no significant predictors of the parent-rated outcome. CONCLUSION: This study showed a small but significant predictive effect of IQ and anxiety on treatment outcome in children with ADHD. CLINICAL IMPLICATIONS: This study supports the idea that for the treatment of ADHD children with comorbid anxiety and higher IQ respond better to the two most used treatments for ADHD.
RCT Entities:
OBJECTIVE: The present study investigated the predictive power of anxiety, IQ, severity of ADHD and parental depression on the outcome of treatment in children with ADHD. METHOD: Fifty children with ADHD (ages 8-12) were randomized to a 10-week treatment of methylphenidate or to a treatment of methylphenidate combined with multimodal behavior therapy. Prior to treatment predictors were assessed. Outcome was assessed separately for parents and teachers on a composite measure of inattentive, hyperactive, oppositional- and conduct disorder symptoms. RESULTS: There was neither a significant difference between the two treatments at baseline nor did treatment condition predict outcome. Therefore the data were collapsed across the two treatments. A combination of anxiety and IQ predicted teacher-rated outcome, explaining 18% of the variance. Higher anxiety and higher IQ's indicated better treatment outcome. There were no significant predictors of the parent-rated outcome. CONCLUSION: This study showed a small but significant predictive effect of IQ and anxiety on treatment outcome in children with ADHD. CLINICAL IMPLICATIONS: This study supports the idea that for the treatment of ADHDchildren with comorbid anxiety and higher IQ respond better to the two most used treatments for ADHD.
Authors: Saskia van der Oord; Pier J M Prins; Jaap Oosterlaan; Paul M G Emmelkamp Journal: Eur Child Adolesc Psychiatry Date: 2006-09-13 Impact factor: 4.785
Authors: L L Greenhill; H B Abikoff; L E Arnold; D P Cantwell; C K Conners; G Elliott; L Hechtman; S P Hinshaw; B Hoza; P S Jensen; J S March; J Newcorn; W E Pelham; J B Severe; J M Swanson; B Vitiello; K Wells Journal: J Am Acad Child Adolesc Psychiatry Date: 1996-10 Impact factor: 8.829
Authors: Elizabeth B Owens; Stephen P Hinshaw; Helen C Kraemer; L Eugene Arnold; Howard B Abikoff; Dennis P Cantwell; C Keith Conners; Glen Elliott; Laurence L Greenhill; Lily Hechtman; Betsy Hoza; Peter S Jensen; John S March; Jeffrey H Newcorn; William E Pelham; Joanne B Severe; James M Swanson; Benedetto Vitiello; Karen C Wells; Timothy Wigal Journal: J Consult Clin Psychol Date: 2003-06
Authors: A Moreno; L Duñó; E Hoekzema; M Picado; L M Martín; J Fauquet; Y Vives-Gilabert; A Bulbena; O Vilarroya Journal: Eur Child Adolesc Psychiatry Date: 2014-01-07 Impact factor: 4.785
Authors: Patrick de Zeeuw; Hugo G Schnack; Janna van Belle; Juliette Weusten; Sarai van Dijk; Marieke Langen; Rachel M Brouwer; Herman van Engeland; Sarah Durston Journal: PLoS One Date: 2012-04-20 Impact factor: 3.240