| Literature DB >> 17876003 |
Catherine L Clark1, Klaudia Kosowska-Shick, Lois M Ednie, Peter C Appelbaum.
Abstract
Testing of 12 pneumococcal strains with differing resistotypes [including tet(M) positive] showed that tigecycline, amoxicillin-clavulanate, imipenem, and ceftriaxone did not select for resistant clones after 50 sequential subcultures. By comparison, azithromycin, clarithromycin, clindamycin, telithromycin, levofloxacin, moxifloxacin, and gemifloxacin did show resistant clones. Tigecycline also yielded a low frequency of resistance in single-step tests compared to all beta-lactams, macrolides/ketolides, and quinolones tested.Entities:
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Year: 2007 PMID: 17876003 PMCID: PMC2151437 DOI: 10.1128/AAC.00827-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191