| Literature DB >> 17876001 |
Anna A Vickers1, Ian Chopra, Alex J O'Neill.
Abstract
Intrinsic novobiocin resistance in Staphylococcus saprophyticus was associated with expression of a novobiocin-resistant form of the drug target protein (GyrB). Site-directed mutagenesis established that resistance depends upon the presence of two specific amino acid residues in GyrB: a glycine at position 85 and a lysine at position 140.Entities:
Mesh:
Substances:
Year: 2007 PMID: 17876001 PMCID: PMC2167987 DOI: 10.1128/AAC.00708-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191