Literature DB >> 17875521

Human T-cell leukemia virus type 1 Tax and cellular transformation.

Jean-Marie Peloponese1, Takao Kinjo, Kuan-Teh Jeang.   

Abstract

Infection of T-cells by human T-cell leukemia virus type 1 (HTLV-1) causes a lymphoproliferative malignancy known as adult T-cell leukemia (ATL). ATL is characterized by abnormal lymphocytes, called flower cells, which have cleaved and convoluted nuclei. Tax, encoded by the HTLV-1 pX region, is a critical nonstructural protein that plays a central role in leukemogenesis; however, the mechanisms of HTLV-1 oncogenesis have not been clarified fully. In this review, we summarize current thinking on how Tax may affect ATL leukemogenesis.

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Year:  2007        PMID： 17875521     DOI： 10.1532/IJH97.07087

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  116 in total

1.  Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

Authors:  G Xiao; E W Harhaj; S C Sun
Journal:  J Biol Chem       Date:  2000-11-03       Impact factor: 5.157

Review 2.  Activation of NF-kappaB by HTLV-I and implications for cell transformation.

Authors:  Shao-Cong Sun; Shoji Yamaoka
Journal:  Oncogene       Date:  2005-09-05       Impact factor: 9.867

Review 3.  Modulation of nuclear factor-kappaB by human T cell leukemia virus type 1 Tax protein: implications for oncogenesis and inflammation.

Authors:  Jean-Marie Peloponese; Man Lung Yeung; Kuan-Teh Jeang
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

4.  Association of MAD2 expression with mitotic checkpoint competence in hepatoma cells.

Authors:  Karen Man-Fong Sze; Yick-Pang Ching; Dong-Yan Jin; Irene Oi-Lin Ng
Journal:  J Biomed Sci       Date:  2004 Nov-Dec       Impact factor: 8.410

5.  Disruption of nucleotide excision repair by the human T-cell leukemia virus type 1 Tax protein.

Authors:  S Y Kao; S J Marriott
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

Review 6.  Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context.

Authors:  David G Johnson; James Degregori
Journal:  Curr Mol Med       Date:  2006-11       Impact factor: 2.222

7.  Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression.

Authors:  G A Pihan; A Purohit; J Wallace; R Malhotra; L Liotta; S J Doxsey
Journal:  Cancer Res       Date:  2001-03-01       Impact factor: 12.701

8.  Constitutive phosphorylation and turnover of I kappa B alpha in human T-cell leukemia virus type I-infected and Tax-expressing T cells.

Authors:  J Lacoste; L Petropoulos; N Pépin; J Hiscott
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103

Review 9.  Aneuploidy and cancer.

Authors:  Harith Rajagopalan; Christoph Lengauer
Journal:  Nature       Date:  2004-11-18       Impact factor: 49.962

10.  Discovery of adult T-cell leukemia.

Authors:  Kiyoshi Takatsuki
Journal:  Retrovirology       Date:  2005-03-02       Impact factor: 4.602
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  25 in total

Review 1.  Human pathogens and the host cell SUMOylation system.

Authors:  Peter Wimmer; Sabrina Schreiner; Thomas Dobner
Journal:  J Virol       Date:  2011-11-09       Impact factor: 5.103

2.  The HTLV-1 hbz antisense gene indirectly promotes tax expression via down-regulation of p30(II) mRNA.

Authors:  Gunjan Choudhary; Lee Ratner
Journal:  Virology       Date:  2010-12-21       Impact factor: 3.616

3.  RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells.

Authors:  Hsin-Ching Lin; Peter J Simon; Riza M Ysla; Steven L Zeichner; Gary Brewer; Arnold B Rabson
Journal:  Virology       Date:  2017-05-04       Impact factor: 3.616

4.  Early spatial and temporal events of human T-lymphotropic virus type 1 spread following blood-borne transmission in a rabbit model of infection.

Authors:  Rashade A H Haynes; Bevin Zimmerman; Laurie Millward; Evan Ware; Christopher Premanandan; Lianbo Yu; Andrew J Phipps; Michael D Lairmore
Journal:  J Virol       Date:  2010-03-10       Impact factor: 5.103

5.  Cyclosporine-induced immune suppression alters establishment of HTLV-1 infection in a rabbit model.

Authors:  Rashade A H Haynes; Evan Ware; Christopher Premanandan; Bevin Zimmerman; Lianbo Yu; Andrew J Phipps; Michael D Lairmore
Journal:  Blood       Date:  2009-11-20       Impact factor: 22.113

Review 6.  Hematopoietic stem cells and retroviral infection.

Authors:  Prabal Banerjee; Lindsey Crawford; Elizabeth Samuelson; Gerold Feuer
Journal:  Retrovirology       Date:  2010-02-04       Impact factor: 4.602

7.  The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.

Authors:  S Mehdi Belgnaoui; Kimberly A Fryrear; Julius O Nyalwidhe; Xin Guo; O John Semmes
Journal:  J Biol Chem       Date:  2010-08-20       Impact factor: 5.157

8.  Adhesion-dependent growth of primary adult T cell leukemia cells with down-regulation of HTLV-I p40Tax protein: a novel in vitro model of the growth of acute ATL cells.

Authors:  Kazuhiro Nagai; Itsuro Jinnai; Tomoko Hata; Tetsuya Usui; Daisuke Sasaki; Kunihiro Tsukasaki; Kazuyuki Sugahara; Yoshitaka Hishikawa; Yasuaki Yamada; Yuetsu Tanaka; Takehiko Koji; Hiroyuki Mano; Shimeru Kamihira; Masao Tomonaga
Journal:  Int J Hematol       Date:  2008-12-02       Impact factor: 2.490

Review 9.  The utilization of humanized mouse models for the study of human retroviral infections.

Authors:  Rachel Van Duyne; Caitlin Pedati; Irene Guendel; Lawrence Carpio; Kylene Kehn-Hall; Mohammed Saifuddin; Fatah Kashanchi
Journal:  Retrovirology       Date:  2009-08-12       Impact factor: 4.602

Review 10.  Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis.

Authors:  Masaya Higuchi; Masahiro Fujii
Journal:  Retrovirology       Date:  2009-12-17       Impact factor: 4.602
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