| Literature DB >> 17875422 |
Jeong Ah Kim1, Un Sil Jeon, Min Seong Kwon, Sun Woo Lim, H Moo Kwon.
Abstract
The TonE-binding protein (TonEBP) is a transcriptional activator in the Rel family that includes NFkappaB and NFAT. TonEBP is critical for the development and function of the renal medulla, which is a major regulator of water homeostasis. TonEBP is also implicated in diabetic nephropathy and inflammation. Established methods for biochemical and histochemical detection and functional analysis of TonEBP, including identification of novel TonEBP target genes, are described for those who are interested in investigating function and regulation of TonEBP.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17875422 DOI： 10.1016/S0076-6879(07)28014-0
Source DB: PubMed Journal: Methods Enzymol ISSN： 0076-6879 Impact factor: 1.600