Literature DB >> 17874573

[Features of bronchial tuberculosis--an analysis of 103 cases].

Atsuhisa Tamura1, Akira Hebisawa, Kimihiko Masuda, Masahiro Shimada, Makiko Kunogi, Yugo Kaneko, Yoshinori Matsui, Masahiro Kawashima, Junko Suzuki, Haruyuki Ariga, Nobuharu Ohshima, Hirotoshi Matsui, Hideaki Nagai, Shinobu Akagawa, Naohiro Nagayama, Yoshiko Kawabe, Kazuko Machida, Atsuyuki Kurashima, Yutsuki Nakajima, Hideki Yotsumoto.   

Abstract

OBJECTIVES: The aim of this study is to clarify the features of bronchial tuberculosis.
MATERIALS AND METHODS: We analyzed the clinicopathological data from 103 out of 4467 (2.3%) cases of culture positive tuberculosis admitted to the National Hospital Organization Tokyo National Hospital in the period from 1993 to 2004 in which bronchial tuberculosis was confirmed by bronchofiberscopy.
RESULTS: There were 62 women and 41 men, and 53 cases were less than 50 years old. The most common symptom, namely cough was observed in 70 cases, while 79 cases showed III1 to III2 on roentgenographic examination, and 81 cases were smear-positive for acid-fast bacilli in the sputum. Regarding the bronchofiberscopic findings, ulcers were detected in 60 cases, and the major site of bronchial tuberculosis was in the left main bronchus (35 cases). The number of the cases in which the time span from the onset of symptoms to diagnosis took over 3 months was 29, and 26 of them were "doctor's delay" cases which had a history of medical consultation resulting in diagnosis and treatment of other diseases, such as bronchial asthma (7 cases). There were 41 cases in which the second bronchofiberscopic findings have been reviewed, and regardless of the length of the span from the onset to diagnosis, the first bronchofiberscopy mostly revealed ulcer within 1 month after the start of treatment for tuberculosis, and 3 months after the start of treatment, many patients developed fibrous scars. Between 1999 to 2004, the first bronchofiberscopies were usually performed within 2 weeks to 1 month after the start of the treatment in contrast to the cases admitted between 1993 to 1998 in which bronchofribroscopy was mainly performed before the start of the treatment. However, there were no differences in the findings due to the timing of bronchofiberscopy.
CONCLUSION: The clinical characteristics of bronchial tuberculosis have not changed, and the delay of diagnosis of bronchial tuberculosis due to doctor's delay also continues to be an important issue today. In patients showing positive sputum smear for mycobacteria, the timing of bronchofiberscopy, although required upon medical examination, is considered to be more appropriately performed from 2 weeks to 1 month after the start of treatment from the view point of nosocomial tuberculosis infection control strategy.

Entities:  

Mesh:

Year:  2007        PMID: 17874573

Source DB:  PubMed          Journal:  Kekkaku        ISSN: 0022-9776


  2 in total

1.  Bronchoscopic local steroid spray to prevent bronchial tuberculosis-induced cicatricial bronchial stenosis: A case series.

Authors:  Daizo Yaguchi; Motoshi Ichikawa; Masato Shizu; Noriko Inoue; Daisuke Kobayashi; Naoyuki Imai
Journal:  Medicine (Baltimore)       Date:  2018-07       Impact factor: 1.889

2.  Bronchoscopic balloon dilatation combined with laser cauterization of high and long segmental tracheal stenosis secondary to endobronchial tuberculosis: A case report.

Authors:  Jun Hanaoka; Masatugu Ohuchi; Ryosuke Kaku; Keigo Okamoto; Yasuhiko Ohshio
Journal:  Respir Med Case Rep       Date:  2019-07-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.