Literature DB >> 17872812

Carpal tunnel syndrome and vitamin B6.

Milly Ryan-Harshman1, Walid Aldoori.   

Abstract

QUESTION: A 42-year-old woman with carpal tunnel syndrome tells you she has started taking a vitamin B6 supplement to relieve her symptoms. Her work in an automotive parts department involves both lifting moderately heavy packages and typing at a computer terminal. What does the research indicate about vitamin B6 as a treatment option, and what health issues should you discuss with this patient? ANSWER: Although its effectiveness is controversial, vitamin B6 is often used as a conservative and adjunct therapy in treatment of carpal tunnel syndrome. Many patients attempt to treat their symptoms with vitamin B6 on their own. Vitamin B6 at less than 200 mg daily is not likely to cause any adverse effects, but patients should be monitored for changes in symptoms, particularly when high doses are taken over long periods.

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Year:  2007        PMID: 17872812      PMCID: PMC1949298     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  9 in total

Review 1.  What can family physicians offer patients with carpal tunnel syndrome other than surgery? A systematic review of nonsurgical management.

Authors:  Felicity Goodyear-Smith; Bruce Arroll
Journal:  Ann Fam Med       Date:  2004 May-Jun       Impact factor: 5.166

2.  Biochemical evidence for a deficiency of vitamin B6 in the carpal tunnel syndrome based on a crossover clinical study.

Authors:  K Folkers; J Ellis; T Watanabe; S Saji; M Kaji
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

Review 3.  Carpal tunnel syndrome: current theory, treatment, and the use of B6.

Authors:  Gregory Holm; Linda E Moody
Journal:  J Am Acad Nurse Pract       Date:  2003-01

4.  Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial.

Authors:  G R Spooner; H B Desai; J F Angel; B A Reeder; J R Donat
Journal:  Can Fam Physician       Date:  1993-10       Impact factor: 3.275

Review 5.  Pharmacotherapy of carpal tunnel syndrome.

Authors:  Paola de Pablo; Jeffrey N Katz
Journal:  Expert Opin Pharmacother       Date:  2003-06       Impact factor: 3.889

Review 6.  Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review.

Authors:  Elaine Aufiero; Todd P Stitik; Patrick M Foye; Boqing Chen
Journal:  Nutr Rev       Date:  2004-03       Impact factor: 7.110

7.  Response of vitamin B-6 deficiency and the carpal tunnel syndrome to pyridoxine.

Authors:  J M Ellis; K Folkers; M Levy; S Shizukuishi; J Lewandowski; S Nishii; H A Schubert; R Ulrich
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

8.  Brief communication: effect of pharmacologic doses of vitamin B6 on carpal tunnel syndrome, electroencephalographic results, and pain.

Authors:  A L Bernstein; J S Dinesen
Journal:  J Am Coll Nutr       Date:  1993-02       Impact factor: 3.169

9.  Carpal tunnel syndrome and vitamin B6.

Authors:  M L Kasdan; C Janes
Journal:  Plast Reconstr Surg       Date:  1987-03       Impact factor: 4.730

  9 in total
  4 in total

1.  Effect of vitamin b6 on clinical symptoms and electrodiagnostic results of patients with carpal tunnel syndrome.

Authors:  Mahnaz Talebi; Sasan Andalib; Shohreh Bakhti; Hormoz Ayromlou; Alireza Aghili; Ashraf Talebi
Journal:  Adv Pharm Bull       Date:  2013-08-20

2.  Clinical usefulness of oral supplementation with alpha-lipoic Acid, curcumin phytosome, and B-group vitamins in patients with carpal tunnel syndrome undergoing surgical treatment.

Authors:  Giorgio Pajardi; Paola Bortot; Veronica Ponti; Chiara Novelli
Journal:  Evid Based Complement Alternat Med       Date:  2014-01-19       Impact factor: 2.629

3.  Efficacy of dietary supplement with nutraceutical composed combined with extremely-low-frequency electromagnetic fields in carpal tunnel syndrome.

Authors:  Teresa Paolucci; Giulia Piccinini; Sveva Maria Nusca; Gabriella Marsilli; Alice Mannocci; Giuseppe La Torre; Vincenzo Maria Saraceni; Maria Chiara Vulpiani; Ciro Villani
Journal:  J Phys Ther Sci       Date:  2018-06-12

Review 4.  The multifaceted role of vitamin B6 in cancer: Drosophila as a model system to investigate DNA damage.

Authors:  Roberto Contestabile; Martino Luigi di Salvo; Victoria Bunik; Angela Tramonti; Fiammetta Vernì
Journal:  Open Biol       Date:  2020-03-25       Impact factor: 6.411

  4 in total

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