Literature DB >> 17872672

Are new agents used to treat rheumatoid arthritis safe to take during pregnancy? Organization of Teratology Information Specialists (OTIS) study.

Christina Chambers, Gideon Koren, Zuhre N Tutuncu, Diana Johnson, Kenneth L Jones.   

Abstract

QUESTION: I have a patient planning pregnancy who has resistant rheumatoid arthritis that will require treatment with some of the "new" medications. Which ones are safe to use during pregnancy, and which ones do we know enough about to tell whether they are safe or not? ANSWER: For most new disease-modifying biologic medications, we have few data on safety. More and more reassuring data are accumulating on azathioprine and cyclosporine. When you treat this patient, you can help in gathering such data by contacting the Organization of Teratology Information Specialists' Autoimmune Disease in Pregnancy study through Motherisk at 877 311-8972.

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Year:  2007        PMID: 17872672      PMCID: PMC1949070     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  11 in total

1.  Efficacy and safety of a combined rituximab chemotherapy during pregnancy.

Authors:  M Herold; S Schnohr; H Bittrich
Journal:  J Clin Oncol       Date:  2001-07-15       Impact factor: 44.544

2.  Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.

Authors:  N M Buchanan; E Toubi; M A Khamashta; F Lima; S Kerslake; G R Hughes
Journal:  Ann Rheum Dis       Date:  1996-07       Impact factor: 19.103

Review 3.  Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease.

Authors:  U Mahadevan; S Kane; W J Sandborn; R D Cohen; K Hanson; J P Terdiman; D G Binion
Journal:  Aliment Pharmacol Ther       Date:  2005-03-15       Impact factor: 8.171

4.  Ocular toxicity and antenatal exposure to chloroquine or hydroxychloroquine for rheumatic diseases.

Authors:  G Klinger; Y Morad; C A Westall; C Laskin; K A Spitzer; G Koren; S Ito; R J Buncic
Journal:  Lancet       Date:  2001-09-08       Impact factor: 79.321

5.  Neural tube defects in relation to use of folic acid antagonists during pregnancy.

Authors:  S Hernández-Díaz; M M Werler; A M Walker; A A Mitchell
Journal:  Am J Epidemiol       Date:  2001-05-15       Impact factor: 4.897

6.  Pregnancy outcome following first trimester exposure to chloroquine.

Authors:  M Levy; D Buskila; D D Gladman; M B Urowitz; G Koren
Journal:  Am J Perinatol       Date:  1991-05       Impact factor: 1.862

7.  Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis.

Authors:  Jeffry A Katz; Christian Antoni; Gregory F Keenan; Deirdre E Smith; Stephen J Jacobs; Gary R Lichtenstein
Journal:  Am J Gastroenterol       Date:  2004-12       Impact factor: 10.864

8.  Safety of rituximab therapy during the first trimester of pregnancy: a case history.

Authors:  Eva Kimby; Asgerdur Sverrisdottir; Göran Elinder
Journal:  Eur J Haematol       Date:  2004-04       Impact factor: 2.997

9.  Pregnancy in ulcerative colitis.

Authors:  O H Nielsen; B Andreasson; S Bondesen; S Jarnum
Journal:  Scand J Gastroenterol       Date:  1983-09       Impact factor: 2.423

10.  The use of disease modifying antirheumatic drugs in women with rheumatoid arthritis of childbearing age: a survey of practice patterns and pregnancy outcomes.

Authors:  Eliza F Chakravarty; Deanna Sanchez-Yamamoto; Thomas M Bush
Journal:  J Rheumatol       Date:  2003-02       Impact factor: 4.666

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  4 in total

Review 1.  [Ophthalmic agents during pregnancy and breastfeeding].

Authors:  T Ness; W Paulus
Journal:  Ophthalmologe       Date:  2012-03       Impact factor: 1.059

Review 2.  Ocular changes during pregnancy.

Authors:  Friederike Mackensen; Wolfgang E Paulus; Regina Max; Thomas Ness
Journal:  Dtsch Arztebl Int       Date:  2014-08-18       Impact factor: 5.594

Review 3.  The treatment of rheumatoid arthritis during pregnancy.

Authors:  Rosamund Partlett; Euthalia Roussou
Journal:  Rheumatol Int       Date:  2010-12-01       Impact factor: 2.631

4.  Pregnancy outcomes after exposure to tocilizumab: A retrospective analysis of 61 patients in Japan.

Authors:  Ken Nakajima; Omi Watanabe; Mayumi Mochizuki; Ayako Nakasone; Nobuhiko Ishizuka; Atsuko Murashima
Journal:  Mod Rheumatol       Date:  2016-03-04       Impact factor: 3.023

  4 in total

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