| Literature DB >> 17870533 |
Claire L Arthurs1, James Raftery, Helen L Whitby, Roger C Whitehead, Natasha S Wind, Ian J Stratford.
Abstract
The synthesis of 6-epi-COTC, a diastereoisomer of Streptomyces metabolite 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC), is described. The anti-cancer activities of the novel analogue, in racemic and enantiomerically pure forms, are presented.Entities:
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Year: 2007 PMID： 17870533 DOI： 10.1016/j.bmcl.2007.07.070
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823