Literature DB >> 17870023

Syphilitic tonsillitis presenting as an ulcerated tonsillar tumor with ipsilateral lymphadenopathy.

David Oddó1, Gonzalo Carrasco, Felipe Capdeville, María Fernanda Ayala.   

Abstract

We describe a 49-year-old man who presented with a cervical mass of a week's evolution, which clinically mimicked a tumoral expansion. Physical examination showed a left cervical mass of 6 x 4 x 2 cm, associated to a left ulcerated tonsillar tumor. The presumptive diagnosis was a tonsillar cancer with lymph node involvement. An amygdalectomy and a frozen section biopsy of the cervical tumor were performed. The biopsy displayed a reactive lymphadenopathy with follicular and interfollicular hyperplasia rich in plasma cells, epithelioid areas, and an outstanding parcel fibrosis of subcapsular, interfollicular, and perifollicular distribution associated to an isolated focus of polymorphonuclear leukocytes and obliterative parietal angiovascular proliferation. The tonsil presented a similar but ulcerated process. These results suggested an infectious reactive process, probably luetic. A Warthin-Starry stain revealed spirochetes in the tonsillar ulcer. Laboratory examinations revealed a positive VDRL test and negative serology for HIV. In conclusion, a primary syphilis of the oropharyngeal tonsil with a syphilic lymphadenopathy was diagnosed. The literature about tonsillar syphilis is reviewed.

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Year:  2007        PMID: 17870023     DOI: 10.1016/j.anndiagpath.2006.04.002

Source DB:  PubMed          Journal:  Ann Diagn Pathol        ISSN: 1092-9134            Impact factor:   2.090


  4 in total

Review 1.  Syphilis: the renaissance of an old disease with oral implications.

Authors:  Giuseppe Ficarra; Roman Carlos
Journal:  Head Neck Pathol       Date:  2009-07-22

2.  Oropharyngeal Syphilis: Imaging and Pathologic Findings in Two Patients.

Authors:  Enric Ripoll; Carla Montironi; Llucia Alós; Teresa Pujol; Joan Berenguer; Laura Oleaga
Journal:  Head Neck Pathol       Date:  2016-10-03

3.  Secondary Syphilis with Tonsillar and Cervical Lymphadenopathy and a Pulmonary Lesion Mimicking Malignant Lymphoma.

Authors:  Yukiko Komeno; Yasunori Ota; Tomohiko Koibuchi; Yoichi Imai; Kuniko Iihara; Tomiko Ryu
Journal:  Am J Case Rep       Date:  2018-03-04

4.  Klebsiella pneumoniae pharyngitis mimicking malignancy: a diagnostic dilemma.

Authors:  C-F Yeh; W-Y Li; Y-B Hsu
Journal:  Infection       Date:  2014-06-13       Impact factor: 3.553

  4 in total

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