Literature DB >> 17869120

Synthesis and biological activities of quinazoline derivatives with ortho-phenol-quaternary ammonium salt groups.

Lixia Zhang1, Lige Ren, Minghui Bai, Liwei Weng, Jing Huang, Lin Wu, Minggang Deng, Xiang Zhou.   

Abstract

One phenol-quaternary ammonium salt derivative with a flexible linker and three derivatives with a quinazoline moiety are present. Their binding affinities for DNA are discussed and it is clearly demonstrated that this class of phenol-quaternary ammonium salt derivatives could inhibit DNA transcription effectively.

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Year:  2007        PMID: 17869120     DOI: 10.1016/j.bmc.2007.07.053

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  3 in total

1.  A Novel Quinazolinone Derivative as Fluorescence Quenching Off-On Sensor for High Selectivity of Fe(3+).

Authors:  Ailin Yuan; Chunling Zheng; Zhengyu Zhang; Lu Yang; Chao Liu; Haibo Wang
Journal:  J Fluoresc       Date:  2013-12-05       Impact factor: 2.217

Review 2.  Mannich bases in medicinal chemistry and drug design.

Authors:  Gheorghe Roman
Journal:  Eur J Med Chem       Date:  2014-10-30       Impact factor: 6.514

Review 3.  Mannich base-connected syntheses mediated by ortho-quinone methides.

Authors:  Petra Barta; Ferenc Fülöp; István Szatmári
Journal:  Beilstein J Org Chem       Date:  2018-03-06       Impact factor: 2.883

  3 in total

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