Literature DB >> 17868999

Neural stem cells, tumour stem cells and brain tumours: dangerous relationships?

Reto Sutter1, Gokhan Yadirgi, Silvia Marino.   

Abstract

Neural stem cells (NSC) have been implicated not only in brain development and neurogenesis but also in tumourigenesis. Brain tumour stem cells (BTSC) have been isolated from several paediatric or adult human brain tumours, however their origin is still disputed. This review discusses the normal role of NSC in the adult mammalian brain and their anatomical location. It compares the molecular characteristics and the biological behaviour of NSC/BTSC, and describes the molecular pathways involved in controlling self-renewal and maintenance of adult NSC/BTSC and brain tumour development. It also assesses the current hypotheses about the origin of BTSC and the clinical consequences.

Entities:  

Mesh：

Year:  2007        PMID： 17868999     DOI： 10.1016/j.bbcan.2007.07.006

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  Cell cycle regulation, neurogenesis, and depression.

Authors:  Kathryn A Cunningham; Cheryl S Watson
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-12       Impact factor: 11.205

Review 2.  An overview of the role of cancer stem cells in spine tumors with a special focus on chordoma.

Authors:  Mojdeh Safari; Alireza Khoshnevisan
Journal:  World J Stem Cells       Date:  2014-01-26       Impact factor: 5.326

3.  Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures.

Authors:  Karina Kristoffersen; Mette Villingshøj; Hans Skovgaard Poulsen; Marie-Thérése Stockhausen
Journal:  Cancer Biol Ther       Date:  2013-05-10       Impact factor: 4.742

4.  GBM secretome induces transient transformation of human neural precursor cells.

Authors:  Chitra Venugopal; X Simon Wang; Branavan Manoranjan; Nicole McFarlane; Sara Nolte; Meredith Li; Naresh Murty; K W Michael Siu; Sheila K Singh
Journal:  J Neurooncol       Date:  2012-07-01       Impact factor: 4.130

5.  Inhibitory activities of trichostatin a in U87 glioblastoma cells and tumorsphere-derived cells.

Authors:  Felipe de Almeida Sassi; Lílian Caesar; Mariane Jaeger; Carolina Nör; Ana Lucia Abujamra; Gilberto Schwartsmann; Caroline Brunetto de Farias; Algemir Lunardi Brunetto; Patrícia Luciana da Costa Lopez; Rafael Roesler
Journal:  J Mol Neurosci       Date:  2014-01-25       Impact factor: 3.444

6.  Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas.

Authors:  Jingxin Qiu; Lingbao Ai; Cheppail Ramachandran; Bing Yao; Suhasni Gopalakrishnan; C Robert Fields; Amber L Delmas; Lisa M Dyer; Steven J Melnick; Anthony T Yachnis; Philip H Schwartz; Howard A Fine; Kevin D Brown; Keith D Robertson
Journal:  Lab Invest       Date:  2008-07-07       Impact factor: 5.662

7.  The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

Authors:  Xudong Zhao; Domenico D' Arca; Wei Keat Lim; Manisha Brahmachary; Maria Stella Carro; Thomas Ludwig; Carlos Cordon Cardo; Francois Guillemot; Ken Aldape; Andrea Califano; Antonio Iavarone; Anna Lasorella
Journal:  Dev Cell       Date:  2009-08       Impact factor: 12.270

8.  Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth.

Authors:  Natividad Pozo; Cristina Zahonero; Paloma Fernández; Jose M Liñares; Angel Ayuso; Masatoshi Hagiwara; Angel Pérez; Jose R Ricoy; Aurelio Hernández-Laín; Juan M Sepúlveda; Pilar Sánchez-Gómez
Journal:  J Clin Invest       Date:  2013-05-01       Impact factor: 14.808

9.  Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.

Authors:  Cécile Thirant; Barbara Bessette; Pascale Varlet; Stéphanie Puget; Josette Cadusseau; Silvina Dos Reis Tavares; Jeanne-Marie Studler; David Carlos Silvestre; Aurélie Susini; Chiara Villa; Catherine Miquel; Alexandra Bogeas; Anne-Laure Surena; Amélia Dias-Morais; Nadine Léonard; Françoise Pflumio; Ivan Bièche; François D Boussin; Christian Sainte-Rose; Jacques Grill; Catherine Daumas-Duport; Hervé Chneiweiss; Marie-Pierre Junier
Journal:  PLoS One       Date:  2011-01-28       Impact factor: 3.240

10.  Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.

Authors:  Suyoun Chung; Hanae Suzuki; Takashi Miyamoto; Naofumi Takamatsu; Ayako Tatsuguchi; Koji Ueda; Kyoko Kijima; Yusuke Nakamura; Yo Matsuo
Journal:  Oncotarget       Date:  2012-12
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