Literature DB >> 1786802

Homogeneous 5-HT1D recognition sites in the human substantia nigra identified with a new iodinated radioligand.

A T Bruinvels1, B Landwehrmeyer, C Waeber, J M Palacios, D Hoyer.   

Abstract

The novel iodinated radioligand, serotonin-5-O-carboxymethyl-glycyl[125I] tyrosinamide, was used for binding studies with membranes of human substantia nigra. Evidence is provided for the existence in this tissue of a homogeneous population of recognition sites with the pharmacological profile of the 5-HT1D site.

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Year:  1991        PMID： 1786802     DOI： 10.1016/0014-2999(91)90257-q

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  4 in total

1.  5-HT1D binding sites in various species: similar pharmacological profile in dog, monkey, calf, guinea-pig and human brain membranes.

Authors:  A T Bruinvels; H Lery; J Nozulak; J M Palacios; D Hoyer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-09       Impact factor: 3.000

2.  "5-HT1R" or 5-HT1D sites? Evidence for 5-HT1D binding sites in rabbit brain.

Authors:  D Hoyer; H Lery; C Waeber; A T Bruinvels; J Nozulak; J M Palacios
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-09       Impact factor: 3.000

3.  Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain.

Authors:  A T Bruinvels; J M Palacios; D Hoyer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-06       Impact factor: 3.000

4.  On the nature of the 5-HT receptor subtype inhibiting acetylcholine release in the guinea-pig ileum.

Authors:  M J Ramírez; J Del Río; E Cenarruzabeitia; B Lasheras
Journal:  Br J Pharmacol       Date:  1994-09       Impact factor: 8.739
  4 in total

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