OBJECTIVE: To observe therapeutic effect and safety of acupuncture at the five-zangshu for treatment of perimenopausal syndrome (PMS). METHODS:Forty cases of PMS were randomly divided into a treatment group and a control group, 20 cases in each group. The treatment group were treated with acupuncture at the five-zangshu and the control group with oral administration of Premarin tablets. The therapeutic effects and changes of Kupperman scores, and serum estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) levels before and after treatment were observed. RESULTS: The total effective rate was 90. 0% in the treatment group which was better than 65.0% in the control group (P<0. 05). After treatment, serum E2 level significantly increased (P<0.01), with a significant difference between the two groups (P<0.05), and with a significant difference between the two groups in Kupperman symptom score index (MI) after treatment (P<0.05). CONCLUSION: Therapeutic effect of acupuncture at the five-zangshu is better than that of Premarin for treatment of perimenopausal syndrome.
RCT Entities:
OBJECTIVE: To observe therapeutic effect and safety of acupuncture at the five-zangshu for treatment of perimenopausal syndrome (PMS). METHODS: Forty cases of PMS were randomly divided into a treatment group and a control group, 20 cases in each group. The treatment group were treated with acupuncture at the five-zangshu and the control group with oral administration of Premarin tablets. The therapeutic effects and changes of Kupperman scores, and serum estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) levels before and after treatment were observed. RESULTS: The total effective rate was 90. 0% in the treatment group which was better than 65.0% in the control group (P<0. 05). After treatment, serum E2 level significantly increased (P<0.01), with a significant difference between the two groups (P<0.05), and with a significant difference between the two groups in Kupperman symptom score index (MI) after treatment (P<0.05). CONCLUSION: Therapeutic effect of acupuncture at the five-zangshu is better than that of Premarin for treatment of perimenopausal syndrome.