Literature DB >> 1785175

[The characteristics of the long-term continuous cultivation of a cell line chronically infected with the human immunodeficiency virus type-1].

O A Mamaeva, O A Pliasunova, T R Proniaeva, A G Pokrovskiĭ, V K Tkachev, E V Karamov, I A Rudneva.   

Abstract

A chronically HIV-1-infected culture of continuous human monocytes producing infectious virus during long-term continuous cultivation (over 200 passages) without the addition of noninfected cells was generated. HIV-1 produced by this culture had typical morphology and complete set of virus-specific proteins. This cell line is proposed for use as an additional model for the evaluation of antiviral effects of various drugs.

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Year:  1991        PMID: 1785175

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN: 0507-4088


  2 in total

1.  Nonintegrated circular forms of the HIV-1 provirus DNA in experimental HIV infection.

Authors:  N M Gashnikova; O A Plyasunova; O A Mamaeva; N V Fedyuk; A G Pokrovskii
Journal:  Dokl Biochem Biophys       Date:  2001 Mar-Apr       Impact factor: 0.788

2.  Construction of an artificial immunogen, a candidate DNA vaccine encoding multiple CTL epitopes of HIV-1.

Authors:  S I Bazhan; P A Belavin; S V Seregin; N K Danilyuk; I N Babkina; L I Karpenko; N A Nekrasova; L R Lebedev; A P Agafonov; G M Ignat'ev; A A Il'ichev; L S Sandakhchiev
Journal:  Dokl Biochem Biophys       Date:  2004 Mar-Apr       Impact factor: 0.788

  2 in total

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