Literature DB >> 17851604

Novel application of Leuckart-Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library.

Sung-Chan Lee1, Seung Bum Park.   

Abstract

A novel and efficient strategy has been developed to synthesize privileged tetrahydro-1,4-benzodiazepines with excellent yields and purities; this synthetic pathway was established by the revitalization of the Leuckart-Wallach (LW) reaction via solid-phase synthesis.

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Year:  2007        PMID: 17851604     DOI: 10.1039/b709768a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart-Wallach type reaction.

Authors:  Suvarna Bokale-Shivale; Mohammad A Amin; Rajiv T Sawant; Marc Y Stevens; Lewend Turanli; Adam Hallberg; Suresh B Waghmode; Luke R Odell
Journal:  RSC Adv       Date:  2020-12-23       Impact factor: 3.361

  1 in total

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