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Literature DB >> 17851393

Synthesis of new 1,3-disubstituted-2,3-dihydro-1H-naphth[1,2e][1,3]oxazines.

Abstract

1,3-Disubstituted-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines were prepared through the ring-closure reactions of the aminobenzylnaphthols with substituted aryl- and heteroarylaldehydes.

Entities: Chemical

Mesh：

Substances：
Naphthols
Oxazines

Year: 2007 PMID： 17851393 PMCID： PMC6149346 DOI： 10.3390/12030345

Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411

3 in total

1. Solvent-free asymmetric aminoalkylation of electron-rich aromatic compounds: stereoselective synthesis of aminoalkylnaphthols by crystallization-induced asymmetric transformation.

Authors: C Cimarelli; A Mazzanti; G Palmieri; E Volpini
Journal: J Org Chem Date: 2001-07-13 Impact factor: 4.354

2. Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.

Authors: Jeffrey N Joyce; Steve Presgraves; Lynn Renish; Sabinne Borwege; Tracy Osredkar; Diane Hagner; Maria Replogle; Mateo PazSoldan; Mark J Millan
Journal: Exp Neurol Date: 2003-11 Impact factor: 5.330

3. Novel 6-aryl-1,4-dihydrobenzo[d]oxazine-2-thiones as potent, selective, and orally active nonsteroidal progesterone receptor agonists.

Authors: Puwen Zhang; Eugene A Terefenko; Andrew Fensome; Jay Wrobel; Richard Winneker; Zhiming Zhang
Journal: Bioorg Med Chem Lett Date: 2003-04-07 Impact factor: 2.823

3 in total

Synthesis of new 1,3-disubstituted-2,3-dihydro-1H-naphth[1,2e][1,3]oxazines.

1. Solvent-free asymmetric aminoalkylation of electron-rich aromatic compounds: stereoselective synthesis of aminoalkylnaphthols by crystallization-induced asymmetric transformation.

2. Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.

3. Novel 6-aryl-1,4-dihydrobenzo[d]oxazine-2-thiones as potent, selective, and orally active nonsteroidal progesterone receptor agonists.

1. 1,3-Di-3-pyridyl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazine.

Review 2. Recent development in the synthesis of heterocycles by 2-naphthol-based multicomponent reactions.

3. 8-Bromo-1,3-diphenyl-2,3-dihydro-1H-naphtho-[1,2-e][1,3]oxazine.