Literature DB >> 1785135

Investigating protein conformation, dynamics and folding with monoclonal antibodies.

M E Goldberg1.   

Abstract

Monoclonal antibodies with thoroughly characterized target specificities can be used as powerful probes of protein conformation. In addition to providing information on the relative arrangement of the domains in the native molecule, they can also be used to monitor both early and late stages of protein folding and conformational changes related to enzyme action.

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Year:  1991        PMID： 1785135     DOI： 10.1016/0968-0004(91)90148-o

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  10 in total

1.  Antibody-detected folding: kinetics of surface epitope formation are distinct from other folding phases.

Authors:  C S Raman; R Jemmerson; B T Nall
Journal:  Protein Sci       Date:  2000-01       Impact factor: 6.725

2.  Isolation and characterization of monoclonal antibodies that inhibit hepatitis C virus NS3 protease.

Authors:  T Ueno; S Misawa; Y Ohba; M Matsumoto; M Mizunuma; N Kasai; K Tsumoto; I Kumagai; H Hayashi
Journal:  J Virol       Date:  2000-07       Impact factor: 5.103

3.  A role for serine-175 in modulating the molecular conformation of calponin.

Authors:  J P Jin; M P Walsh; C Sutherland; W Chen
Journal:  Biochem J       Date:  2000-09-01       Impact factor: 3.857

4.  The heart-specific NH2-terminal extension regulates the molecular conformation and function of cardiac troponin I.

Authors:  Shirin Akhter; Zhiling Zhang; J-P Jin
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-12-02       Impact factor: 4.733

5.  Effects of surface wettability and contact time on protein adhesion to biomaterial surfaces.

Authors:  Li-Chong Xu; Christopher A Siedlecki
Journal:  Biomaterials       Date:  2007-04-12       Impact factor: 12.479

Review 6.  Overview of the purification of recombinant proteins.

Authors:  Paul T Wingfield
Journal:  Curr Protoc Protein Sci       Date:  2015-04-01

7.  Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease.

Authors:  M Bogdanov; W Dowhan
Journal:  EMBO J       Date:  1998-09-15       Impact factor: 11.598

8.  Microtiter plate monoclonal antibody epitope analysis of Ca2+- and Mg2+-induced conformational changes in troponin C.

Authors:  Jian-Ping Jin; Stephen M Chong; M Moazzem Hossain
Journal:  Arch Biochem Biophys       Date:  2007-08-06       Impact factor: 4.013

9.  Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T.

Authors:  Shirin Akhter; J-P Jin
Journal:  FEBS Open Bio       Date:  2015-01-13       Impact factor: 2.693

10.  Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab.

Authors:  Mercè Farràs; Ramón Román; Marc Camps; Joan Miret; Óscar Martínez; Xavier Pujol; Antoni Casablancas; Jordi Joan Cairó
Journal:  BMC Mol Cell Biol       Date:  2020-01-21
  10 in total

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