Literature DB >> 17851102

Give a dog a genome.

Cathryn Mellersh1.   

Abstract

In 2004 the dog became only the fifth mammal to have its entire genome fully sequenced. The canine genome was sequenced in the hope that it would help scientists understand the complex evolutionary mechanisms that shape genes and genomes and provide a powerful tool for identifying genetic factors that contribute to human health and disease. It is expected that over the coming years the genome of man's best friend will help in the understanding of the genetic cause of many inherited diseases that humans and dogs have in common. Not only of obvious benefit to humans, these studies will enable the development of DNA diagnostic tests that breeders can use to identify which of their dogs carry mutations that put them at risk of developing particular conditions and thus, over time, eliminate those diseases from the breed.

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Year:  2007        PMID: 17851102     DOI: 10.1016/j.tvjl.2007.06.029

Source DB:  PubMed          Journal:  Vet J        ISSN: 1090-0233            Impact factor:   2.688


  2 in total

1.  Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed.

Authors:  Oliver P Forman; Jacques Penderis; Claudia Hartley; Louisa J Hayward; Sally L Ricketts; Cathryn S Mellersh
Journal:  PLoS Genet       Date:  2012-01-12       Impact factor: 5.917

2.  Pedigree and Molecular Analyses in the Assessment of Genetic Variability of the Polish Greyhound.

Authors:  Małgorzata Goleman; Ireneusz Balicki; Anna Radko; Iwona Rozempolska-Rucińska; Grzegorz Zięba
Journal:  Animals (Basel)       Date:  2021-01-31       Impact factor: 2.752

  2 in total

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