| Literature DB >> 17850988 |
D U Owu1, E E Ben, A B Antai, E A Ekpe, P M Udia.
Abstract
Aqueous extract of Vernonia amygdalina infused intragastrically at a dose of 10 mg/ml to rats induced a significant increase in acid output which was reduced by, ranitidine (5 mg/kg b.w.) or atropine (1.2 microMol/kg b.w.). Moreover the extract evoked a dose-dependent contraction of the guinea pig ileum at a dose range of 0.6 mg/ml to 66 mg/ml which was inhibited by atropine (2.4 x 10(-8)-2.4 x 10(-6) M).Entities:
Mesh：
Substances：
Year: 2007 PMID： 17850988 DOI： 10.1016/j.fitote.2007.07.011
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882