| Literature DB >> 17850156 |
Hong Yee Cheung1, Wing-Yiu Yu, Fuk Loi Lam, Terry T-L Au-Yeung, Zhongyuan Zhou, Tak Hang Chan, Albert S C Chan.
Abstract
Chiral ferrocenyl heterobidentate P/S ligands bearing both central and planar chirality were prepared from (S)-Ugi's amine via a three-step modular synthesis. Through systematic screening and optimization, L8 was found to be the best ligand for Pd-catalyzed asymmetric allylic alkylation of indoles with ee's up to 96% being attained.Entities:
Year: 2007 PMID： 17850156 DOI： 10.1021/ol7018532
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005