| Literature DB >> 17850093 |
Sergey V Ryabukhin1, Andrey S Plaskon, Eugeniy N Ostapchuk, Dmitriy M Volochnyuk, Oleg V Shishkin, Alexander N Shivanyuk, Andrey A Tolmachev.
Abstract
The chlorotrimethylsilane-promoted Biginelli type reactions of aldehydes, thiourea, and cyanoketones led to a diverse set of tetrahydropyrimidine-2(1H)-thiones. Under similar conditions, thioureas, benzaldehyde, and cyanoacetamide reacted to give first representatives of hexahydro-5H-pyrimido[5,4-e][1,3]thiazin-5-ones in high preparative yield.Entities:
Year: 2007 PMID: 17850093 DOI: 10.1021/ol701782v
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005