D J Gallagher1, A Duffy, J McCaffrey. 1. Department of Medical Oncology, Mater Misercordiae University Hospital, Eccles St, Dublin 7, Ireland. Daithig@gmail.com
Abstract
BACKGROUND: Wilms' tumour is a very rare adult malignancy representing 1% of adult renal tumours. It is however the most common renal tumour of childhood, and adult patients are treated in accordance with paediatric protocols. AIM: To review modern day management of adult Wilms' tumour. METHODS: We report a case of adult Wilms' tumour and discuss the management including the use of newer treatment modalities. RESULTS: Following diagnostic nephrectomy, our patient was treated with chemotherapy in accordance with North American paediatric protocols and PET scanning was used to diagnose early relapse. CONCLUSION: In the absence of randomised controlled data, central reporting of cases of adult Wilms' Tumour may help improve management. The incorporation of newer chemotherapeutic agents, high-dose therapy and PET scanning into treatment protocols should improve outcome for these patients.
BACKGROUND:Wilms' tumour is a very rare adult malignancy representing 1% of adult renal tumours. It is however the most common renal tumour of childhood, and adult patients are treated in accordance with paediatric protocols. AIM: To review modern day management of adult Wilms' tumour. METHODS: We report a case of adult Wilms' tumour and discuss the management including the use of newer treatment modalities. RESULTS: Following diagnostic nephrectomy, our patient was treated with chemotherapy in accordance with North American paediatric protocols and PET scanning was used to diagnose early relapse. CONCLUSION: In the absence of randomised controlled data, central reporting of cases of adult Wilms' Tumour may help improve management. The incorporation of newer chemotherapeutic agents, high-dose therapy and PET scanning into treatment protocols should improve outcome for these patients.
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