Literature DB >> 17847070

Quantification of normal range of inflammatory changes in morphologically normal pediatric muscle.

Hemlata Varsani1, Katy R Newton, Charles K Li, Brian Harding, Janice L Holton, Lucy R Wedderburn.   

Abstract

The aim of this study was to define normal ranges of histological features in pediatric muscle in comparison with muscle demonstrating inflammatory changes. Sixteen pediatric muscle biopsy samples, considered normal by standard histology, were analyzed for the presence of inflammatory cells, and the expression of neonatal myosin and major histocompatibility complex (MHC) Class 1. Normal findings were defined for each feature. These data will facilitate quantitative analysis of inflammatory changes in pediatric muscle biopsy.

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Year:  2008        PMID: 17847070     DOI: 10.1002/mus.20898

Source DB:  PubMed          Journal:  Muscle Nerve        ISSN: 0148-639X            Impact factor:   3.217


  6 in total

1.  A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies.

Authors:  Neil Martin; Petra Krol; Sally Smith; Kevin Murray; Clarissa A Pilkington; Joyce E Davidson; Lucy R Wedderburn
Journal:  Rheumatology (Oxford)       Date:  2010-09-07       Impact factor: 7.580

2.  Maternal microchimerism in muscle biopsies from children with juvenile dermatomyositis.

Authors:  Yi Ye; Berendine van Zyl; Hemlata Varsani; Lucy R Wedderburn; Athimalaipet Ramanan; Kathleen M Gillespie
Journal:  Rheumatology (Oxford)       Date:  2012-01-23       Impact factor: 7.580

3.  CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

Authors:  Christopher J M Piper; Meredyth G Ll Wilkinson; Claire T Deakin; Georg W Otto; Stefanie Dowle; Chantal L Duurland; Stuart Adams; Emiliano Marasco; Elizabeth C Rosser; Anna Radziszewska; Rita Carsetti; Yiannis Ioannou; Philip L Beales; Daniel Kelberman; David A Isenberg; Claudia Mauri; Kiran Nistala; Lucy R Wedderburn
Journal:  Front Immunol       Date:  2018-06-22       Impact factor: 7.561

4.  Morphometric analyses of normal pediatric brachial biceps and quadriceps muscle tissue.

Authors:  Adriana M E Sallum; Hemlata Varsani; Janice L Holton; Suely K N Marie; Lucy R Wedderburn
Journal:  Histol Histopathol       Date:  2013-02-08       Impact factor: 2.303

5.  Myeloid related protein induces muscle derived inflammatory mediators in juvenile dermatomyositis.

Authors:  Kiran Nistala; Hemlata Varsani; Helmut Wittkowski; Thomas Vogl; Petra Krol; Vanita Shah; Kamel Mamchaoui; Paul A Brogan; Johannes Roth; Lucy R Wedderburn
Journal:  Arthritis Res Ther       Date:  2013-09-23       Impact factor: 5.156

6.  Expression of myxovirus-resistance protein A: a possible marker of muscle disease activity and autoantibody specificities in juvenile dermatomyositis.

Authors:  S Soponkanaporn; C T Deakin; P W Schutz; L R Marshall; S A Yasin; C M Johnson; E Sag; S L Tansley; N J McHugh; L R Wedderburn; T S Jacques
Journal:  Neuropathol Appl Neurobiol       Date:  2018-06-04       Impact factor: 8.090

  6 in total

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