OBJECTIVE: To examine patients attended and diagnosed with bipolar disorder (BD) at a child and adolescent psychiatry service; to record age of diagnosis and age of onset, and to study clinical differences between prepubertal and adolescent onset groups. METHODS: All patients currently attended for BD type I, type II or non specified BD were reviewed and divided into two age groups: prepubertal onset (beginning before age 13) and adolescent onset (beginning at or above age 13). RESULTS: The sample were 43 patients with BD. Fourteen (32.6%) with prepubertal onset and 29 (67.4%) with adolescent onset. Time between onset of symptoms and diagnosis was longer in the prepubertal onset group (1.2 years versus 0.8 years respectively, P = .05). Patients with prepubertal onset BD more frequently presented previous symptoms such as irritability and conduct problems and had a higher rate of comorbidity (more frequently attention-deficit/hyperactivity disorder-ADHD). The adolescent onset group more often presented psychotic symptoms. CONCLUSION: The clinical characteristics of patients with bipolar disorder differ according to whether onset is prepubertal or adolescent.
OBJECTIVE: To examine patients attended and diagnosed with bipolar disorder (BD) at a child and adolescent psychiatry service; to record age of diagnosis and age of onset, and to study clinical differences between prepubertal and adolescent onset groups. METHODS: All patients currently attended for BD type I, type II or non specified BD were reviewed and divided into two age groups: prepubertal onset (beginning before age 13) and adolescent onset (beginning at or above age 13). RESULTS: The sample were 43 patients with BD. Fourteen (32.6%) with prepubertal onset and 29 (67.4%) with adolescent onset. Time between onset of symptoms and diagnosis was longer in the prepubertal onset group (1.2 years versus 0.8 years respectively, P = .05). Patients with prepubertal onset BD more frequently presented previous symptoms such as irritability and conduct problems and had a higher rate of comorbidity (more frequently attention-deficit/hyperactivity disorder-ADHD). The adolescent onset group more often presented psychotic symptoms. CONCLUSION: The clinical characteristics of patients with bipolar disorder differ according to whether onset is prepubertal or adolescent.
Authors: Manon Hj Hillegers; Catrien G Reichart; Marjolein Wals; Frank C Verhulst; Johan Ormel; Willem A Nolen Journal: Bipolar Disord Date: 2005-08 Impact factor: 6.744
Authors: Eric Mick; Joseph Biederman; Stephen V Faraone; Kate Murray; Janet Wozniak Journal: J Child Adolesc Psychopharmacol Date: 2003 Impact factor: 2.576
Authors: Janet Wozniak; Michael Monuteaux; Jennifer Richards; Kathryn E Lail; Stephen V Faraone; Joseph Biederman Journal: Biol Psychiatry Date: 2003-06-01 Impact factor: 13.382
Authors: Joseph Biederman; Eric Mick; Janet Wozniak; Michael C Monuteaux; Maribel Galdo; Stephen V Faraone Journal: Biol Psychiatry Date: 2003-06-01 Impact factor: 13.382