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Literature DB >> 17846578

Synthesis and biological evaluation of rigid polycyclic derivatives of the Diels-Alder adduct tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione.

Felicia Megumi Ito¹, Jacqueline Marques Petroni, Dênis Pires de Lima, Adilson Beatriz, Maria Rita Marques, Manoel Odorico de Moraes, Letícia Veras Costa-Lotufo, Raquel Carvalho Montenegro, Hemerson Iury Ferreira Magalhães, Cláudia do O Pessoa.

Abstract

Part of our research program concentrates on the discovery of new bioactive compounds prepared either by total synthesis or molecular transformation of compounds with bioactivity profiles. In this work we have focused our interest on chemical transformations of the Diels-Alder adduct tricyclo[6.2.1.0(2,7)]undeca-4,9-dien-3,6-dione in order to obtain cage-like compounds and derivatives, followed by an evaluation of their biological activity.

Entities: Chemical

Mesh：

Substances：
Polycyclic Compounds

Year: 2007 PMID： 17846578 PMCID： PMC6149379 DOI： 10.3390/12020271

Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411

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