Literature DB >> 178442

Tumor-associated thymidine kinase in the sera of rats with transplanted hepatomas.

A Taylor, E G Hewitt, O W Jones.   

Abstract

A cytoplasmic form of thymidine kinase was detected in sera from rats bearing Morris hepatoma 7777. Polyacrylamide electrophoretic properties demonstrate similarity between the serum enzyme extracted from hepatoma tissue. This form of thymidine kinase has also been described in normal human fetal tissue and a variety of human tumor cells. The results suggest that serum isoenzymes of thymidine kinase may be a useful adjunctive test for the presence of certain types of malignant tumors.

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Year:  1976        PMID: 178442

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  4 in total

1.  Elevated serum thymidine kinase activity in patients with acute viral hepatitis.

Authors:  K Tanaka; T Sishido; M Morimoto; S Inoue; Y Takamura; M Masumura
Journal:  Gastroenterol Jpn       Date:  1993-02

2.  Stabilization of SV40 transformed human fibroblast cytoplasmic thymidine kinase by ATP.

Authors:  P N Porter; D Bull; O W Jones
Journal:  Mol Cell Biochem       Date:  1981-02-26       Impact factor: 3.396

3.  Experimental studies on potentiation of the antitumor activity of 5-fluorouracil with 3'-azido-3'-deoxythymidine for the gastric cancer cell line MKN28 in vivo.

Authors:  C Yasuda; M Kato; D Kuroda; H Ohyanagi
Journal:  Jpn J Cancer Res       Date:  1997-01

4.  Thymidine Kinase Type 1 and C-Reactive Protein Concentrations in Dogs with Spontaneously Occurring Cancer.

Authors:  K A Selting; R Ringold; B Husbands; P O Pithua
Journal:  J Vet Intern Med       Date:  2016-05-23       Impact factor: 3.333

  4 in total

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