Literature DB >> 17828627

Creatine supplementation and cognitive performance in elderly individuals.

Terry McMorris1, Gregorsz Mielcarz, Roger C Harris, Jonathan P Swain, Alan Howard.   

Abstract

The purpose of this study was to examine the effect of creatine supplementation on the cognitive performance of elderly people. Participants were divided into two groups, which were tested on random number generation, forward and backward number and spatial recall, and long-term memory tasks to establish a baseline level. Group 1 (n = 15) were given 5 g four times a day of placebo for 1 week, followed by the same dosage of creatine for the second week. Group 2 (n = 17) were given placebo both weeks. Participants were retested at the end of each week. Results showed a significant effect of creatine supplementation on all tasks except backward number recall. It was concluded that creatine supplementation aids cognition in the elderly.

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Year:  2007        PMID: 17828627     DOI: 10.1080/13825580600788100

Source DB:  PubMed          Journal:  Neuropsychol Dev Cogn B Aging Neuropsychol Cogn        ISSN: 1382-5585


  26 in total

1.  Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials.

Authors:  Konstantinos I Avgerinos; Nikolaos Spyrou; Konstantinos I Bougioukas; Dimitrios Kapogiannis
Journal:  Exp Gerontol       Date:  2018-04-25       Impact factor: 4.032

2.  Creatine-induced activation of antioxidative defence in myotube cultures revealed by explorative NMR-based metabonomics and proteomics.

Authors:  Jette F Young; Lotte B Larsen; Anders Malmendal; Niels Chr Nielsen; Ida K Straadt; Niels Oksbjerg; Hanne C Bertram
Journal:  J Int Soc Sports Nutr       Date:  2010-02-04       Impact factor: 5.150

Review 3.  ISSN exercise & sports nutrition review update: research & recommendations.

Authors:  Chad M Kerksick; Colin D Wilborn; Michael D Roberts; Abbie Smith-Ryan; Susan M Kleiner; Ralf Jäger; Rick Collins; Mathew Cooke; Jaci N Davis; Elfego Galvan; Mike Greenwood; Lonnie M Lowery; Robert Wildman; Jose Antonio; Richard B Kreider
Journal:  J Int Soc Sports Nutr       Date:  2018-08-01       Impact factor: 5.150

4.  Chronic high-dose creatine has opposing effects on depression-related gene expression and behavior in intact and sex hormone-treated gonadectomized male and female rats.

Authors:  Patricia J Allen; Joseph F DeBold; Maribel Rios; Robin B Kanarek
Journal:  Pharmacol Biochem Behav       Date:  2015-01-03       Impact factor: 3.533

Review 5.  The creatine kinase system and pleiotropic effects of creatine.

Authors:  Theo Wallimann; Malgorzata Tokarska-Schlattner; Uwe Schlattner
Journal:  Amino Acids       Date:  2011-03-30       Impact factor: 3.520

6.  Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution.

Authors:  Adam D Pfefferle; Lisa R Warner; Catrina W Wang; William J Nielsen; Courtney C Babbitt; Olivier Fedrigo; Gregory A Wray
Journal:  J Hum Evol       Date:  2010-12-28       Impact factor: 3.895

Review 7.  Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

Authors:  Patricia J Allen
Journal:  Neurosci Biobehav Rev       Date:  2012-03-24       Impact factor: 8.989

Review 8.  Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review.

Authors:  Richard B Kreider; Ralf Jäger; Martin Purpura
Journal:  Nutrients       Date:  2022-02-28       Impact factor: 5.717

9.  Dietary creatine and cognitive function in U.S. adults aged 60 years and over.

Authors:  Sergej M Ostojic; Darinka Korovljev; Valdemar Stajer
Journal:  Aging Clin Exp Res       Date:  2021-04-17       Impact factor: 3.636

10.  Mitochondrial therapy for Parkinson's disease: neuroprotective pharmaconutrition may be disease-modifying.

Authors:  Richard Kones
Journal:  Clin Pharmacol       Date:  2010-09-17
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