| Literature DB >> 17828120 |
M A Charnaia, T V Klypa, Iu A Morozov, N P Shmerko, V G Gladysheva, A A Andriianova.
Abstract
Effects of different doses and lots of protamine sulfate on hemostasis system after cardiac operations with artificial circulation are analyzed. Overall 982 patients underwent cardiac operations with artificial circulation. Quality and purity of protamine may be the causes of side effects. Negative effect of high doses of protamine on hemostasis system is demonstrated. Thrombocyte dysfunction is the main cause of intensive postoperative bleeding after administration of protamine high doses.Entities:
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Year: 2007 PMID： 17828120
Source DB: PubMed Journal: Khirurgiia (Mosk) ISSN： 0023-1207