Literature DB >> 17827687

Effect of the benzylic structure of lignan on antioxidant activity.

Satoshi Yamauchi1, Takuya Sugahara, Junko Matsugi, Tatsushi Someya, Toshiya Masuda, Taro Kishida, Koichi Akiyama, Masafumi Maruyama.   

Abstract

The effect of the benzylic structure of lignan on antioxidant activity was evaluated. Secoisolariciresinol (1) and 3,4-bis(4-hydroxy-3-methoxybenzyl)tetrahydrofuran (2), which have two secondary benzylic positions without oxygen, showed the highest antioxidant activity. Optically active verrucosin (4) was synthesized for the first time in this experiment.

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Year:  2007        PMID： 17827687     DOI： 10.1271/bbb.70275

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  3 in total

1.  Isochaihulactone protects PC12 cell against H(2)O(2) induced oxidative stress and exerts the potent anti-aging effects in D-galactose aging mouse model.

Authors:  Sung-Liang YU; Shih-bin LIN; Yung-luen YU; Min-hui CHIEN; Kuo-jung SU; Ching-Ju LIN; Tzong-der WAY; Giou-Teng YIANG; Chai-Ching LIN; De-Chuan CHAN; Horng-Jyh HARN; Yi-Lin Sophia CHEN
Journal:  Acta Pharmacol Sin       Date:  2010-11-01       Impact factor: 6.150

2.  The antidepressant effect of secoisolariciresinol, a lignan-type phytoestrogen constituent of flaxseed, on ovariectomized mice.

Authors:  Ying-Feng Wang; Zhi-Kun Xu; Dong-Hui Yang; Hai-Yan Yao; Bao-Shan Ku; Xiao-Qing Ma; Cheng-Zhi Wang; Shu-Lin Liu; Shao-Qing Cai
Journal:  J Nat Med       Date:  2012-04-03       Impact factor: 2.343

3.  Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs).

Authors:  Om P Mishra; Nicholas Simmons; Sonia Tyagi; Ralph Pietrofesa; Vladimir V Shuvaev; Roman A Valiulin; Philipp Heretsch; K C Nicolaou; Melpo Christofidou-Solomidou
Journal:  Bioorg Med Chem Lett       Date:  2013-08-02       Impact factor: 2.823
  3 in total

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