Literature DB >> 17827001

Design and synthesis of novel antibacterial peptide-resin conjugates.

Won-Mi Cho1, Bishnu Prasad Joshi, Hyeongjin Cho, Keun-Hyeung Lee.   

Abstract

We synthesized a novel peptide-resin conjugate by immobilizing beta-sheet antibacterial peptide on PEG-PS resin. The peptide-resin conjugate, similar to cationic antimicrobial peptides, demonstrated unique properties such as potent antibacterial activity, no hemolytic activity, lipid membrane perturbation activity, and potent synergism with vancomycin. Specially, the peptide-resin conjugate showed a more increased lipid membrane perturbation activity in comparison to unbound beta-sheet antibacterial peptide.

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Year:  2007        PMID： 17827001     DOI： 10.1016/j.bmcl.2007.08.056

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Effectiveness of antimicrobial peptide immobilization for preventing perioperative cornea implant-associated bacterial infection.

Authors:  Xiao Wei Tan; Tze Wei Goh; P Saraswathi; Chan Lwin Nyein; Melina Setiawan; Andri Riau; R Lakshminarayanan; Shouping Liu; Donald Tan; Roger W Beuerman; Jodhbir S Mehta
Journal:  Antimicrob Agents Chemother       Date:  2014-06-23       Impact factor: 5.191

2.  Antimicrobial functionalized genetically engineered spider silk.

Authors:  Sílvia C Gomes; Isabel B Leonor; João F Mano; Rui L Reis; David L Kaplan
Journal:  Biomaterials       Date:  2011-03-31       Impact factor: 12.479

3.  Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum.

Authors:  Mojtaba Bagheri; Michael Beyermann; Margitta Dathe
Journal:  Antimicrob Agents Chemother       Date:  2008-12-22       Impact factor: 5.191

Review 4.  Nanomedicine as an emerging approach against intracellular pathogens.

Authors:  Andrea L Armstead; Bingyun Li
Journal:  Int J Nanomedicine       Date:  2011-12-09

5.  Antimicrobial activity of Piper gaudichaudianum Kuntze and its synergism with different antibiotics.

Authors:  Mariele Caroline Marques Nogueira Puhl; Diógenes Aparício Garcia Cortez; Tânia Ueda-Nakamura; Celso Vataru Nakamura; Benedito Prado Dias Filho
Journal:  Molecules       Date:  2011-12-01       Impact factor: 4.411

6.  The intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5.

Authors:  Carlos Lopez-Abarrategui; Viviana Figueroa-Espi; Maria B Lugo-Alvarez; Caroline D Pereira; Hilda Garay; João Arg Barbosa; Rosana Falcão; Linnavel Jiménez-Hernández; Osvaldo Estévez-Hernández; Edilso Reguera; Octavio L Franco; Simoni C Dias; Anselmo J Otero-Gonzalez
Journal:  Int J Nanomedicine       Date:  2016-08-09

7.  Antimicrobial peptide modification of biomaterials using supramolecular additives.

Authors:  Sabrina Zaccaria; Ronald C van Gaal; Martijn Riool; Sebastian A J Zaat; Patricia Y W Dankers
Journal:  J Polym Sci A Polym Chem       Date:  2018-08-09       Impact factor: 2.702
  7 in total

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